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High-quality antibody necessary for transcriptional control signal

Anti human PPAR gamma common mouse monoclonal antibody


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PPAR gamma : Peroxisome Proliferator-Activated Receptor gamma

Background

Peroxisome proliferator-activated receptor gamma (PPARg; NR1C3) is a member of orphan nuclear receptor. Oxidized metabolites of linoleic acid, 9- hydroxyctadienoic acid (9-HODE) and 13-HODE are activators and ligands of PPARg. PPARg is expressed in white adipose tissue, intestinal mucosa, colon, spleen, monocytes, macrophages, retina, cartilage, osteoclast and skeletal muscle. PPARg plays important roles in lipid and glucose metabolism, and have been implicated in obesity-related metabolic diseases such as hyperlipidemia, insulin resistance, and coronary artery disease. Three members were called PPARa, b, g. Three N-terminal isoforms, called g1, g2 and g3, are known to arise by alternative splicing and promoter usage from the PPARg gene. RXR is an obligate partner for PPAR

Application

<Recommended Concentration>
In order to obtain the best results, optimal working dilutions should be determined by each individual user
  Western Blot : 1 ug/mL
  ELISA : 12 ng/mL
  Immunoprecipitation : Decide by use
  Supershift Assay : Decide by use
  Chromatin immunoprecipitation : Decide by use
  Immunohistochemistry : 10 ug/mL


Rat adipose cell

Rat placenta

<Reference>
1. Tanaka T.,et all., Atheroscler Thronb, 9(5) 233-241, 2002.        

Specificity

This antibody specifically recognizes human PPAR gamma1 and 2 and cross reacts with mouse and rat PPAR gamma1 and 2.
This antibody does not recognize human PPAR alpha and delta.

Product List

Product Name Cat# Quantity Price

Anti PPAR(γ) common, Human (Mouse)  DataSheet

PPX-PP-A3409A-00

0.1 ML ¥50,000
$667

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