記事ID ： 3675

リコンビナント活性型プロテインキナーゼ

メーカー名：SignalChem Pharmaceuticals,Inc.

全長(full-length)で変異なし(mutation free)の活性型プロテインキナーゼは幅広く販売しております。

背景

プロテインキナーゼが関与するシグナルカスケードにおける異常は、癌、循環器疾患、神経疾患、炎症、代謝疾患を含む、様々なヒトの疾患の発症に関与することは、広く知られています。　近年の診断におけるプロテインキナーゼインヒビターの活躍により、患者の全身への影響を最小限にとどめつつ、予後を改善するような特異的なインヒビターを同定するための創薬研究に、力が注がれています。

ハイスループットスクリーニングを成功させるための重要な因子は、ターゲットとなるキナーゼの選択ですが、シグナルケム社の高度精製キナーゼターゲットは、全長(full-length)で変異なし(mutation free)のリコンビナントタンパク質で、in vivoでは起こらないようなリン酸化などの修飾によって、キナーゼを活性化させる必要はありません！

特長

High Specific Activity
Increased Signal-to-Noise = GREATER UTILITY
High Purity
Decreased Interference = LARGER SUCCESS
Full Length
Functional Domains Intact = INCREASED EFFICIENCY
Mutation Free
Void of Activating Mutations = CONFIDENCE IN YOUR RESULTS

商品内容

Higher Enzymatic Activity Than The Competition - No Activating Mutations

Purity Evaluation

Vmax - Km Studies

リコンビナントプロテインキナーゼ

品名	メーカー	品番	包装	希望販売価格
AKT1 (PKB α), Active, Human	SCP	A16-10G	5 UG	￥38,000
AKT1 (PKB α), Active, Human	SCP	A16-10G	10 UG	￥54,000
AKT2, Active, Human	SCP	A17-10G	5 UG	￥54,000
AKT2, Active, Human	SCP	A17-10G	10 UG	￥78,000
AKT2, Active, Human	SCP	A17-10H	5 UG	￥54,000
AKT2, Active, Human	SCP	A17-10H	10 UG	￥78,000
AKT3, Active, Human	SCP	A18-10G	5 UG	￥54,000
AKT3, Active, Human	SCP	A18-10G	10 UG	￥78,000
BLK, Active, Human	SCP	B02-10G	5 UG	￥54,000
BLK, Active, Human	SCP	B02-10G	10 UG	￥78,000
BMX, Active, Human	SCP	B07-10G	5 UG	￥54,000
BMX, Active, Human	SCP	B07-10G	10 UG	￥78,000
BMX, Active, Human	SCP	B07-10G	20 UG	販売終了
CAMK1 β, Active, Mouse	SCP	C08-10G	5 UG	￥54,000
CAMK1 β, Active, Mouse	SCP	C08-10G	10 UG	￥78,000
CAMK1 δ, Active, Human	SCP	C09-10G	5 UG	￥54,000
CAMK1 δ, Active, Human	SCP	C09-10G	10 UG	￥78,000
CAMK4, Active, Human	SCP	C15-10G	5 UG	￥54,000
CAMK4, Active, Human	SCP	C15-10G	10 UG	￥78,000
CHK1, Active, Human	SCP	C47-10G	5 UG	￥54,000
CHK1, Active, Human	SCP	C47-10G	10 UG	￥78,000
CHK2, Active, Human	SCP	C48-10G	5 UG	￥54,000
CHK2, Active, Human	SCP	C48-10G	10 UG	￥78,000
CSK, Active, Human	SCP	C63-10G	5 UG	￥54,000
CSK, Active, Human	SCP	C63-10G	10 UG	￥78,000
CK2 α 1, Active, Human	SCP	C70-10G	5 UG	￥54,000
CK2 α 1, Active, Human	SCP	C70-10G	10 UG	￥78,000
FGR, Active, Human	SCP	F10-10G	5 UG	￥54,000
FGR, Active, Human	SCP	F10-10G	10 UG	￥78,000
FRK, Active, Human	SCP	F14-11G	5 UG	￥54,000
FRK, Active, Human	SCP	F14-11G	10 UG	￥78,000
GRK5, Active, Human	SCP	G03-10G	5 UG	￥54,000
GRK5, Active, Human	SCP	G03-10G	10 UG	￥78,000
GSK3 β, Active, Human	SCP	G09-10G	5 UG	￥54,000
GSK3 β, Active, Human	SCP	G09-10G	10 UG	￥78,000
HCK, Active, Human	SCP	H02-11G	5 UG	￥54,000
HCK, Active, Human	SCP	H02-11G	10 UG	￥78,000
LCK, Active, Human	SCP	L03-10G	5 UG	￥54,000
LCK, Active, Human	SCP	L03-10G	10 UG	￥78,000
LYN B, Active, Human	SCP	L13-10G	5 UG	￥54,000
LYN B, Active, Human	SCP	L13-10G	10 UG	￥78,000
ASK1, Active, Human	SCP	M13-11G	5 UG	￥54,000
ASK1, Active, Human	SCP	M13-11G	10 UG	￥78,000
ERK1, Active, Human	SCP	M29-10U	5 UG	￥54,000
ERK1, Active, Human	SCP	M29-10U	10 UG	￥78,000
JNK1, Active, Mouse	SCP	M33-10G	5 UG	￥54,000
JNK1, Active, Mouse	SCP	M33-10G	10 UG	￥78,000
MAPKAPK2, Active, Human	SCP	M40-11G	5 UG	￥54,000
MAPKAPK2, Active, Human	SCP	M40-11G	10 UG	￥78,000
MAPKAPK3, Active, Human	SCP	M41-10G	5 UG	￥54,000
MAPKAPK3, Active, Human	SCP	M41-10G	10 UG	￥78,000
MET, Active, Rat	SCP	M52-11G	5 UG	￥54,000
MET, Active, Rat	SCP	M52-11G	10 UG	￥78,000
NEK2, Active, Human	SCP	N03-10G	5 UG	￥54,000
NEK2, Active, Human	SCP	N03-10G	10 UG	￥78,000
NEK6, Active, Human	SCP	N08-10G	5 UG	￥54,000
NEK6, Active, Human	SCP	N08-10G	10 UG	￥78,000
NEK7, Active, Human	SCP	N09-10G	5 UG	￥54,000
NEK7, Active, Human	SCP	N09-10G	10 UG	￥78,000
TRKA, Active, Human	SCP	N16-11G	5 UG	￥54,000
TRKA, Active, Human	SCP	N16-11G	10 UG	￥78,000
PAK7, Active, Human	SCP	P07-10G	5 UG	￥54,000
PAK7, Active, Human	SCP	P07-10G	10 UG	￥78,000
PDGFR β, Active, Human	SCP	P13-11G	5 UG	￥54,000
PDGFR β, Active, Human	SCP	P13-11G	10 UG	￥78,000
PIM1, Active, Human	SCP	P35-10G	5 UG	￥54,000
PIM1, Active, Human	SCP	P35-10G	10 UG	￥78,000
PIM2, Active, Human	SCP	P36-10G	5 UG	￥54,000
PIM2, Active, Human	SCP	P36-10G	10 UG	￥78,000
PKAc α, Active, Human	SCP	P51-10G	5 UG	￥54,000
PKAc α, Active, Human	SCP	P51-10G	10 UG	￥78,000
PKAc β, Active, Human	SCP	P52-10G	5 UG	￥54,000
PKAc β, Active, Human	SCP	P52-10G	10 UG	￥78,000
PKAc γ, Active, Human	SCP	P53-10G	5 UG	￥54,000
PKAc γ, Active, Human	SCP	P53-10G	10 UG	￥78,000
PKC α, Active, Xenopus	SCP	P61-10G	5 UG	￥38,000
PKC α, Active, Xenopus	SCP	P61-10G	10 UG	￥54,000
PKC β II, Active, Human	SCP	P63-10G	5 UG	￥38,000
PKC β II, Active, Human	SCP	P63-10G	10 UG	￥54,000
PKC δ, Active, Human	SCP	P64-10G	5 UG	￥38,000
PKC δ, Active, Human	SCP	P64-10G	10 UG	￥54,000
PKC ε, Active, Human	SCP	P65-10G	5 UG	￥38,000
PKC ε, Active, Human	SCP	P65-10G	10 UG	￥54,000
PKC γ, Active, Human	SCP	P66-10G	5 UG	￥38,000
PKC γ, Active, Human	SCP	P66-10G	10 UG	￥54,000
PKC η, Active, Human	SCP	P67-10G	5 UG	￥38,000
PKC η, Active, Human	SCP	P67-10G	10 UG	￥54,000
PKC ι, Active, Human	SCP	P68-10G	5 UG	￥38,000
PKC ι, Active, Human	SCP	P68-10G	10 UG	￥54,000
PKC μ, Active, Human	SCP	P72-10G	5 UG	￥38,000
PKC μ, Active, Human	SCP	P72-10G	10 UG	￥54,000
PKC ν, Active, Human	SCP	P73-10G	5 UG	￥38,000
PKC ν, Active, Human	SCP	P73-10G	10 UG	￥54,000
PKC ζ, Active, Human	SCP	P75-10G	5 UG	￥38,000
PKC ζ, Active, Human	SCP	P75-10G	10 UG	￥54,000
PKD2, Active, Human	SCP	P76-10G	5 UG	￥54,000
PKD2, Active, Human	SCP	P76-10G	10 UG	￥78,000
BRK, Active, Human	SCP	P94-10G	5 UG	￥54,000
BRK, Active, Human	SCP	P94-10G	10 UG	￥78,000
RIPK2, Active, Human	SCP	R08-11G	5 UG	￥54,000
RIPK2, Active, Human	SCP	R08-11G	10 UG	￥78,000
RSK1, Active, Human	SCP	R15-10G	5 UG	￥54,000
RSK1, Active, Human	SCP	R15-10G	10 UG	￥78,000
RSK2, Active, Human	SCP	R17-10G	5 UG	￥54,000
RSK2, Active, Human	SCP	R17-10G	10 UG	￥78,000
p70S6K, Active, Human	SCP	R21-10H	5 UG	￥54,000
p70S6K, Active, Human	SCP	R21-10H	10 UG	￥78,000
SGK1, Active, Human	SCP	S06-11G	5 UG	￥54,000
SGK1, Active, Human	SCP	S06-11G	10 UG	￥78,000
SGK2, Active, Human	SCP	S07-10G	5 UG	￥54,000
SGK2, Active, Human	SCP	S07-10G	10 UG	￥78,000
Rous sarcoma virus SRC, Active, Virus	SCP	S19-10G	5 UG	￥54,000
Rous sarcoma virus SRC, Active, Virus	SCP	S19-10G	10 UG	￥78,000
STK3, Active, Human	SCP	S24-10G	5 UG	￥54,000
STK3, Active, Human	SCP	S24-10G	10 UG	￥78,000
ZAP70, Active, Human	SCP	Z02-10G	5 UG	￥54,000
ZAP70, Active, Human	SCP	Z02-10G	10 UG	￥78,000