AKT/PKB シグナル伝達経路(AKT/PKB Pathway)関連キナーゼを各種販売しております。
SignalChem社 高精製度 キナーゼ トップへ戻るAKT/PKB シグナル伝達経路関連商品を各種販売 高精製度キナーゼ ‐ AKT/PKB Pathway
- カテゴリから探す > シグナル伝達 > リン酸化/ユビキチン化/SUMO化 > プロテインキナーゼ
- 研究分野から探す > がん研究 > リン酸化の検出・測定 > リコンビナントキナーゼ
背景
AKT/PKB シグナル伝達経路について
AKT(またはPKB)シグナル伝達経路は、細胞増殖や生存、細胞サイズや栄養素利用への応答性、グルコース代謝、組織浸潤および血管新生など多くの細胞プロセスを調節しており、ここ10年以上に渡って注目されている研究項目です。AKTは細胞外(成長因子およびインスリン)および細胞内(受容体チ ロシンキナーゼ、RasおよびSrc)シグナルの伝達経路において主要な節点として働きます。AKT経路は至るところに存在している分子で、細胞内において基本的な細胞プロセスを調節しています。
セリン/スレオニンキナーゼであるAKTは、AKT経路における主要分子であり、哺乳類では3つのアイソフォーム(AKT1,AKT2およびAKT3)として存在し、PIP3リン脂質セカンドメセンジャー産生に寄与する主要な脂質キナーゼ標的であるPI3Kの下流に位置しています。AKTの活性化には、プレクストリン相同領域を通じたPIP3への結合、PDK1によるThr308でのAKT活性化ループのリン酸化、そしてPDK2によるSer473でのC-末端内のリン酸化が必要です(1)。
多くのヒト悪性疾患において、AKT経路の変化、特にAKT自身における変化が発見されています(2)。AKT、特に恒常的に活性化されたAKTの異所性発現により、トランスジェニックマウスにおいて、細胞の発癌形質転換、腫瘍形成、化学療法抵抗性が誘発されます。
多くの腫瘍および腫瘍細胞においてAKTタンパク質の発現および活性の上昇が見られ、また、AKT自身を調節する多くのタンパク質(例、PI3K、PTEN、Ras、Srcおよびチロシンキナーゼ)もしばしば癌において変異します。
AKTシグナル伝達の阻害は、AKTの上昇を伴う腫瘍細胞の増殖抑制やアポトーシスを引き起こします。ある腫瘍が生存/増殖に際してAKTシグナル伝達に依存することが観察されたことは、癌治療に対して大きな意味を持っており、選択的に腫瘍細胞を殺す可能性を提示しています。近年、コンビナトリアルケミス トリー、ハイスループット、バーチャルスクリーニングおよび伝統的な医薬品化学などにより、AKT経路の阻害剤が数多く同定され、更なる臨床的な有用性が追求されています(3)。
References
1. Vanhaesebroeck, B., et al.: The PI3K-PDK1 connection: More than just a road to PKB. Biochem J. 2000 Mar 15;346 Pt 3:561-76.
2. Altomare, D. A., et al.: Perturbations of the AKT signaling pathway in human cancer. Oncogene. 2005 Nov 14;24(50):7455-64.
3. Kumar, C. C., et al.: AKT crystal structure and AKT-specific inhibitors. Oncogene. 2005 Nov 14;24(50):7493-501
高精製度キナーゼ - AKT/PKB Pathway
品名 | メーカー | 品番 | 包装 | 希望販売価格 |
---|---|---|---|---|
14-3-3 α/β, Human | SCP | Y71-30G | 20 UG |
¥38,000 |
14-3-3 α/β, Human | SCP | Y71-30G | 50 UG |
¥81,000 |
14-3-3 α/β, Human | SCP | Y71-30N | 20 UG |
¥38,000 |
14-3-3 α/β, Human | SCP | Y71-30N | 50 UG |
¥81,000 |
14-3-3 ε, Human | SCP | Y75-30G | 20 UG |
¥38,000 |
14-3-3 ε, Human | SCP | Y75-30G | 50 UG |
¥81,000 |
14-3-3 ε, Human | SCP | Y75-30N | 20 UG |
¥38,000 |
14-3-3 ε, Human | SCP | Y75-30N | 50 UG |
¥81,000 |
14-3-3σ, Human | SCP | Y86-30G | 20 UG |
¥38,000 |
14-3-3σ, Human | SCP | Y86-30G | 50 UG |
¥81,000 |
14-3-3σ, Human | SCP | Y86-30N | 20 UG |
¥38,000 |
14-3-3σ, Human | SCP | Y86-30N | 50 UG |
¥81,000 |
14-3-3θ, Human | SCP | Y84-30G | 20 UG |
¥38,000 |
14-3-3θ, Human | SCP | Y84-30G | 50 UG |
¥81,000 |
14-3-3θ, Human | SCP | Y84-30N | 20 UG |
¥38,000 |
14-3-3θ, Human | SCP | Y84-30N | 50 UG |
¥81,000 |
14-3-3ζ, Human | SCP | Y92-30G | 20 UG |
¥38,000 |
14-3-3ζ, Human | SCP | Y92-30G | 50 UG |
¥81,000 |
14-3-3ζ, Human | SCP | Y92-30N | 20 UG |
¥38,000 |
14-3-3ζ, Human | SCP | Y92-30N | 50 UG |
¥81,000 |
4EBP1, Human | SCP | E35-54BH | 20 UG |
¥52,000 |
4EBP1, Human | SCP | E35-54BH | 50 UG |
¥104,000 |
4EBP1, Human | SCP | E35-54G | 20 UG |
¥52,000 |
4EBP1, Human | SCP | E35-54G | 50 UG |
¥104,000 |
4EBP1, Human | SCP | E35-54H | 20 UG |
¥52,000 |
4EBP1, Human | SCP | E35-54H | 50 UG |
¥104,000 |
AKT (PKB) Substrate | SCP | A05-58 | 1 MG |
¥20,000 |
AKT (SGK) Substrate | SCP | A08-58 | 1 MG |
¥20,000 |
AKT1 Mutant (E17K), Active, Human | SCP | A16-12G | 5 UG |
¥54,000 |
AKT1 Mutant (E17K), Active, Human | SCP | A16-12G | 10 UG |
¥78,000 |
AKT1 (PKB α), Active, Human | SCP | A16-10G | 5 UG |
¥38,000 |
AKT1 (PKB α), Active, Human | SCP | A16-10G | 10 UG |
¥54,000 |
AKT1, Unactive, Human | SCP | A16-14G | 20 UG |
¥52,000 |
AKT1, Unactive, Human | SCP | A16-14G | 50 UG |
¥104,000 |
AKT2 Mutant (E17K), Active, Human | SCP | A17-12G | 5 UG |
¥54,000 |
AKT2 Mutant (E17K), Active, Human | SCP | A17-12G | 10 UG |
¥78,000 |
AKT2 Mutant (R274H), Active, Human | SCP | A17-12BG | 5 UG |
¥54,000 |
AKT2 Mutant (R274H), Active, Human | SCP | A17-12BG | 10 UG |
¥78,000 |
AKT2, Active, Human | SCP | A17-10G | 5 UG |
¥54,000 |
AKT2, Active, Human | SCP | A17-10G | 10 UG |
¥78,000 |
AKT2, Active, Human | SCP | A17-10H | 5 UG |
¥54,000 |
AKT2, Active, Human | SCP | A17-10H | 10 UG |
¥78,000 |
AKT2, Unactive, Human | SCP | A17-14G | 20 UG |
¥52,000 |
AKT2, Unactive, Human | SCP | A17-14G | 50 UG |
¥104,000 |
AKT2, Unactive, Human | SCP | A17-15H | 20 UG |
¥52,000 |
AKT2, Unactive, Human | SCP | A17-15H | 50 UG |
¥104,000 |
AKT3 Mutant (G171R), Active, Human | SCP | A18-12BG | 5 UG |
¥54,000 |
AKT3 Mutant (G171R), Active, Human | SCP | A18-12BG | 10 UG |
¥78,000 |
AKT3, Active, Human | SCP | A18-10G | 5 UG |
¥54,000 |
AKT3, Active, Human | SCP | A18-10G | 10 UG |
¥78,000 |
AKT3, Unactive, Human | SCP | A18-14G | 20 UG |
¥52,000 |
AKT3, Unactive, Human | SCP | A18-14G | 50 UG |
¥104,000 |
ALK1, Active, Human | SCP | A09-11G | 5 UG |
¥54,000 |
ALK1, Active, Human | SCP | A09-11G | 10 UG |
¥78,000 |
ALK2 Mutant (R206H), Active, Human | SCP | A06-12BG | 5 UG |
¥54,000 |
ALK2 Mutant (R206H), Active, Human | SCP | A06-12BG | 10 UG |
¥78,000 |
ALK2, Active, Human | SCP | A06-11G | 5 UG |
¥54,000 |
ALK2, Active, Human | SCP | A06-11G | 10 UG |
¥78,000 |
ALK3 (BMPR1A), Active, Human | SCP | B04-11G | 5 UG |
¥54,000 |
ALK3 (BMPR1A), Active, Human | SCP | B04-11G | 10 UG |
¥78,000 |
ALK4, Active, Human | SCP | A07-11G | 5 UG |
¥54,000 |
ALK4, Active, Human | SCP | A07-11G | 10 UG |
¥78,000 |
ALK6 (BMPR1B), Active, Human | SCP | B05-11G | 5 UG |
¥54,000 |
ALK6 (BMPR1B), Active, Human | SCP | B05-11G | 10 UG |
¥78,000 |
ALK7, Human | SCP | A08-35G | 20 UG |
¥52,000 |
ALK7, Human | SCP | A08-35G | 50 UG |
¥104,000 |
Anti 4EBP1, Human (Rabbit) | SCP | E35-563R | 100 UG |
¥143,000 |
Anti AFX, Human (Rabbit) | SCP | A42-63R | 100 UG |
¥65,000 |
Anti AKT1, (Mouse) , 9A4 | SCP | A16-60M | 25 UG |
¥23,000 |
Anti AKT1, (Mouse) , 9A4 | SCP | A16-60M | 100 UG |
¥90,000 |
Anti AKT1, Human (Rabbit) | SCP | A16-63CR | 100 UG |
¥143,000 |
Anti AKT2/3 (Rabbit) | SCP | A17-63BR | 25 UG |
¥26,000 |
Anti AKT2/3 (Rabbit) | SCP | A17-63BR | 100 UG |
¥95,000 |
Anti AKT3 (Rabbit) | SCP | A18-63R | 25 UG |
¥30,000 |
Anti AKT3 (Rabbit) | SCP | A18-63R | 100 UG |
¥116,000 |
Anti ALK2, Human (Rabbit) | SCP | A06-63R | 100 UG |
¥143,000 |
Anti ALK4, Human (Rabbit) | SCP | A07-63R | 100 UG |
¥143,000 |
Anti ALK7, Human (Rabbit) | SCP | A08-63R | 100 UG |
¥143,000 |
Anti BAG1, Human (Rabbit) | SCP | B05-363BR | 100 UG |
¥143,000 |
Anti BAG1, Human (Rabbit) | SCP | B05-363R | 100 UG |
¥143,000 |
Anti BAX, Human (Rabbit) | SCP | B14-363R | 100 UG |
¥143,000 |
Anti DYRK2, Human (Rabbit) | SCP | D10-63R | 100 UG |
¥143,000 |
Anti EGFR, Human (Rabbit) | SCP | E10-63BR | 100 UG |
¥65,000 |
Anti EGFR, Human (Rabbit) | SCP | E10-63R | 100 UG |
¥65,000 |
Anti FLT3, Human (Rabbit) | SCP | F12-63R | 100 UG |
¥143,000 |
Anti GSK3 α (Rabbit) | SCP | G08-63R | 25 UG |
¥26,000 |
Anti GSK3 α (Rabbit) | SCP | G08-63R | 100 UG |
¥95,000 |
Anti HER2, Human (Rabbit) | SCP | E27-63R | 100 UG |
¥143,000 |
Anti HSP90 β, Human (Rabbit) | SCP | H36-63R | 100 UG |
¥83,000 |
Anti IRS1, Human (Rabbit) | SCP | I40-363R | 100 UG |
¥143,000 |
Anti mTOR, Human (Rabbit) | SCP | F17-63R | 100 UG |
¥65,000 |
Anti p70S6K, Human (Rabbit) | SCP | R21-63BR | 100 UG |
¥65,000 |
Anti p70S6K (Rabbit) | SCP | R21-63R | 25 UG |
¥26,000 |
Anti p70S6K (Rabbit) | SCP | R21-63R | 100 UG |
¥95,000 |
Anti PDFGB, Human (Rabbit) | SCP | P842-63R | 100 UG |
¥143,000 |
Anti PHLPP2, Human (Rabbit) | SCP | P72-263R | 100 UG |
¥143,000 |
Anti 4EBP1, phospho Thr45 (Rabbit) | SCP | E35-365R | 100 UG |
¥78,000 |
Anti AKT1/2/3, phospho Ser473 (Rabbit) | SCP | A16-65BR | 100 UG |
¥89,000 |
Anti AKT1/2/3, phospho Thr308 (Rabbit) | SCP | A16-65R | 100 UG |
¥89,000 |
Anti EGFR, phospho Thr678 (Rabbit) | SCP | E10-65BR | 100 UG |
¥65,000 |
Anti EGFR, phospho Thr693 (Rabbit) | SCP | E10-65CR | 100 UG |
¥65,000 |
Anti EGFR, phospho Tyr1092 (Rabbit) | SCP | E10-65DR | 100 UG |
¥65,000 |
Anti EGFR, phospho Tyr1110 (Rabbit) | SCP | E10-65ER | 100 UG |
¥65,000 |
Anti EGFR, phospho Tyr1197 (Rabbit) | SCP | E10-65FR | 100 UG |
¥78,000 |
Anti GSK3 β, phospho Ser9 (Rabbit) | SCP | G09-65R | 100 UG |
¥78,000 |
Anti HER2, phospho Tyr877 (Rabbit) | SCP | E27-65R | 100 UG |
¥65,000 |
Anti Phosphoserine (Anti pS) (Rabbit) | SCP | S95-65R | 100 UG |
¥91,000 |
Anti Phosphoserine (Anti pS) (Rabbit) Biotin | SCP | S95-65BR | 100 UG |
¥136,000 |
Anti Phosphothreonine (Anti pT) (Rabbit) | SCP | T95-65R | 100 UG |
¥109,000 |
Anti Phosphothreonine (Anti pT) (Rabbit) Biotin | SCP | T95-65BR | 100 UG |
¥136,000 |
Anti Phosphotyrosine (Anti pY) (Rabbit) | SCP | T96-65R | 100 UG |
¥109,000 |
Anti Phosphotyrosine (Anti pY) (Rabbit) Biotin | SCP | T96-65BR | 100 UG |
¥136,000 |
Anti PTEN, Human (Rabbit) | SCP | P23-263BR | 100 UG |
¥143,000 |
Anti Rel A, Human (Rabbit) | SCP | R29-63BR | 100 UG |
¥65,000 |
Anti Rel A, Human (Rabbit) | SCP | R29-63R | 100 UG |
¥65,000 |
Anti SGK1, Human (Rabbit) | SCP | S06-63R | 100 UG |
¥143,000 |
Anti SMAD2, Human (Rabbit) | SCP | S11-63R | 100 UG |
¥83,000 |
Anti TAB1, Human (Rabbit) | SCP | T01-363R | 100 UG |
¥143,000 |
Anti TAK1, Human (Rabbit) | SCP | M15-63R | 100 UG |
¥143,000 |
Anti Trail, Human (Rabbit) | SCP | T880-63R | 100 UG |
¥143,000 |
BAG1, Human | SCP | B05-31G | 20 UG |
¥52,000 |
BAG1, Human | SCP | B05-31G | 50 UG |
¥104,000 |
BAX, Human | SCP | B14-30G | 20 UG |
¥52,000 |
BAX, Human | SCP | B14-30G | 50 UG |
¥104,000 |
BMP-2, Human | SCP | B851-40N | 10 UG |
販売終了 |
BMP-2, Human | SCP | B851-40N | 50 UG |
販売終了 |
BMP-4, Human | SCP | B853-40N | 10 UG |
販売終了 |
BMP-4, Human | SCP | B853-40N | 50 UG |
販売終了 |
BMP2K, Mouse | SCP | B03-11G | 20 UG |
販売終了 |
BMP2K, Mouse | SCP | B03-11G | 50 UG |
販売終了 |
BMPR2, Active, Human | SCP | B06-11H | 5 UG |
販売終了 |
BMPR2, Active, Human | SCP | B06-11H | 10 UG |
販売終了 |
Crosstide | SCP | C51-58 | 1 MG |
¥20,000 |
DYRK2, Active, Human | SCP | D10-10G | 5 UG |
¥54,000 |
DYRK2, Active, Human | SCP | D10-10G | 10 UG |
¥78,000 |
DYRK3, Active, Human | SCP | D11-11G | 5 UG |
¥54,000 |
DYRK3, Active, Human | SCP | D11-11G | 10 UG |
¥78,000 |
DYRKtide | SCP | D96-58 | 1 MG |
¥20,000 |
EEF2K, Active, Human | SCP | E01-10G | 5 UG |
¥54,000 |
EEF2K, Active, Human | SCP | E01-10G | 10 UG |
¥78,000 |
EF2tide | SCP | E01-58 | 1 MG |
¥20,000 |
EGFR Mutant (L858R), Active, Human | SCP | E10-12BG | 5 UG |
販売終了 |
EGFR Mutant (L858R), Active, Human | SCP | E10-12BG | 10 UG |
販売終了 |
EGFR Mutant (L861Q), Active, Human | SCP | E10-12CG | 5 UG |
¥54,000 |
EGFR Mutant (L861Q), Active, Human | SCP | E10-12CG | 10 UG |
¥78,000 |
EGFR Mutant (T790M L858R), Active, Human | SCP | E10-12DG | 5 UG |
販売終了 |
EGFR Mutant (T790M L858R), Active, Human | SCP | E10-12DG | 10 UG |
販売終了 |
EGFR Mutant (T790M), Active, Human | SCP | E10-12EG | 5 UG |
販売終了 |
EGFR Mutant (T790M), Active, Human | SCP | E10-12EG | 10 UG |
販売終了 |
EGFR, Active, Human | SCP | E10-11G | 5 UG |
販売終了 |
EGFR, Active, Human | SCP | E10-11G | 10 UG |
販売終了 |
FAK, Active, Human | SCP | P91-10G | 5 UG |
¥54,000 |
FAK, Active, Human | SCP | P91-10G | 10 UG |
¥78,000 |
FAK, Active, Human | SCP | P91-11H | 5 UG |
¥54,000 |
FAK, Active, Human | SCP | P91-11H | 10 UG |
¥78,000 |
FGFR1 (FLT2), Active, Human | SCP | F04-11G | 5 UG |
¥54,000 |
FGFR1 (FLT2), Active, Human | SCP | F04-11G | 10 UG |
¥78,000 |
FGFR1 Mutant (V561M), Active, Human | SCP | F04-13G | 5 UG |
¥54,000 |
FGFR1 Mutant (V561M), Active, Human | SCP | F04-13G | 10 UG |
¥78,000 |
FGFR2, Active, Human | SCP | F05-11G | 5 UG |
¥54,000 |
FGFR2, Active, Human | SCP | F05-11G | 10 UG |
¥78,000 |
FGFR3 Mutant (K650E), Active, Human | SCP | F06-12CG | 5 UG |
¥54,000 |
FGFR3 Mutant (K650E), Active, Human | SCP | F06-12CG | 10 UG |
¥78,000 |
FGFR3, Active, Human | SCP | F06-11G | 5 UG |
¥54,000 |
FGFR3, Active, Human | SCP | F06-11G | 10 UG |
¥78,000 |
FGFR4, Active, Human | SCP | F07-11G | 5 UG |
¥54,000 |
FGFR4, Active, Human | SCP | F07-11G | 10 UG |
¥78,000 |
FKBP1A, Human | SCP | F37-30G | 20 UG |
¥52,000 |
FKBP1A, Human | SCP | F37-30G | 50 UG |
¥104,000 |
FLT1, Active, Human | SCP | F11-11G | 5 UG |
¥54,000 |
FLT1, Active, Human | SCP | F11-11G | 10 UG |
¥78,000 |
FLT3 Mutant (D835Y), Active, Human | SCP | F12-12BG | 5 UG |
¥54,000 |
FLT3 Mutant (D835Y), Active, Human | SCP | F12-12BG | 10 UG |
¥78,000 |
FLT3, Active, Human | SCP | F12-11G | 5 UG |
¥54,000 |
FLT3, Active, Human | SCP | F12-11G | 10 UG |
¥78,000 |
FLT4, Active, Human | SCP | F13-11G | 5 UG |
¥54,000 |
FLT4, Active, Human | SCP | F13-11G | 10 UG |
¥78,000 |
FRS3, Human | SCP | F80-30G | 20 UG |
¥52,000 |
FRS3, Human | SCP | F80-30G | 50 UG |
¥104,000 |
GS Peptide | SCP | G60-58 | 1 MG |
¥20,000 |
GSK3 α, Active, Human | SCP | G08-10G | 5 UG |
¥54,000 |
GSK3 α, Active, Human | SCP | G08-10G | 10 UG |
¥78,000 |
GSK3 β, Active, Human | SCP | G09-10G | 5 UG |
¥54,000 |
GSK3 β, Active, Human | SCP | G09-10G | 10 UG |
¥78,000 |
GSK3 β, Active, Human | SCP | G09-10H | 5 UG |
¥54,000 |
GSK3 β, Active, Human | SCP | G09-10H | 10 UG |
¥78,000 |
GSK3 β, Unactive, Human | SCP | G09-14G | 20 UG |
¥52,000 |
GSK3 β, Unactive, Human | SCP | G09-14G | 50 UG |
¥104,000 |
GSK3 Substrate, Human | SCP | G50-58 | 1 MG |
¥25,000 |
HER2, Active, Human | SCP | E27-11G | 5 UG |
¥54,000 |
HER2, Active, Human | SCP | E27-11G | 10 UG |
¥78,000 |
HER4, Active, Human | SCP | E29-11G | 5 UG |
¥54,000 |
HER4, Active, Human | SCP | E29-11G | 10 UG |
¥78,000 |
HSP90 α, Human | SCP | H36-50H | 20 UG |
¥52,000 |
HSP90 α, Human | SCP | H36-50H | 50 UG |
¥104,000 |
HSP90 β, Human | SCP | H36-54H | 20 UG |
¥52,000 |
HSP90 β, Human | SCP | H36-54H | 50 UG |
¥104,000 |
IGF1R, Active, Human | SCP | I02-11H | 5 UG |
¥54,000 |
IGF1R, Active, Human | SCP | I02-11H | 10 UG |
¥78,000 |
IκBα, Human | SCP | I20-30G | 20 UG |
¥52,000 |
IκBα, Human | SCP | I20-30G | 50 UG |
¥104,000 |
IκBα, Human | SCP | I20-31G | 20 UG |
¥52,000 |
IκBα, Human | SCP | I20-31G | 50 UG |
¥104,000 |
IκBβ, Human | SCP | I21-30G | 20 UG |
¥52,000 |
IκBβ, Human | SCP | I21-30G | 50 UG |
¥104,000 |
IKKtide, Human | SCP | I33-58 | 1 MG |
¥20,000 |
IL-2, Human | SCP | I862-40N | 10 UG |
販売終了 |
IL-2, Human | SCP | I862-40N | 50 UG |
販売終了 |
IL-8 (72AA), Human | SCP | I868-40N | 10 UG |
販売終了 |
IL-8 (72AA), Human | SCP | I868-40N | 50 UG |
販売終了 |
InsR, Active, Human | SCP | I08-11G | 5 UG |
¥54,000 |
InsR, Active, Human | SCP | I08-11G | 10 UG |
¥78,000 |
IP-10, Human | SCP | I838-40N | 10 UG |
販売終了 |
IP-10, Human | SCP | I838-40N | 50 UG |
販売終了 |
IRR, Active, Human | SCP | I07-11G | 5 UG |
¥54,000 |
IRR, Active, Human | SCP | I07-11G | 10 UG |
¥78,000 |
IRS1, Human | SCP | I40-31G | 20 UG |
¥52,000 |
IRS1, Human | SCP | I40-31G | 50 UG |
¥104,000 |
IRS1, Human | SCP | I40-35G | 20 UG |
¥52,000 |
IRS1, Human | SCP | I40-35G | 50 UG |
¥104,000 |
KDR, Active, Human | SCP | K01-11G | 5 UG |
¥54,000 |
KDR, Active, Human | SCP | K01-11G | 10 UG |
¥78,000 |
Leptin, Human | SCP | L833-40N | 10 UG |
販売終了 |
Leptin, Human | SCP | L833-40N | 50 UG |
販売終了 |
LYN A, Active, Human | SCP | L13-18G | 5 UG |
¥54,000 |
LYN A, Active, Human | SCP | L13-18G | 10 UG |
¥78,000 |
LYN B, Active, Human | SCP | L13-10G | 5 UG |
¥54,000 |
LYN B, Active, Human | SCP | L13-10G | 10 UG |
¥78,000 |
MDM2, Human | SCP | M45-31BH | 20 UG |
¥25,000 |
MDM2, Human | SCP | M45-31BH | 50 UG |
¥38,000 |
MDM2, Human | SCP | M45-31G | 20 UG |
¥52,000 |
MDM2, Human | SCP | M45-31G | 50 UG |
¥104,000 |
MDM4, Human | SCP | M47-31BH | 20 UG |
¥52,000 |
MDM4, Human | SCP | M47-31BH | 50 UG |
¥104,000 |
Modified AKT Substrate | SCP | A05-58B | 1 MG |
¥25,000 |
Modified AKT Substrate II | SCP | A05-58C | 1 MG |
¥25,000 |
Modified SGKtide | SCP | S08-58B | 1 MG |
¥25,000 |
MST1, Active, Human | SCP | S25-10G | 5 UG |
¥54,000 |
MST1, Active, Human | SCP | S25-10G | 10 UG |
¥78,000 |
MST3, Active, Human | SCP | S42-11G | 5 UG |
¥54,000 |
MST3, Active, Human | SCP | S42-11G | 10 UG |
¥78,000 |
MST4, Active, Human | SCP | M59-10G | 5 UG |
¥54,000 |
MST4, Active, Human | SCP | M59-10G | 10 UG |
¥78,000 |
NFKB2, Human | SCP | N13-31G | 20 UG |
¥52,000 |
NFKB2, Human | SCP | N13-31G | 50 UG |
¥104,000 |
p70S6K, Active, Human | SCP | R21-10H | 5 UG |
¥54,000 |
p70S6K, Active, Human | SCP | R21-10H | 10 UG |
¥78,000 |
p70S6K, Unactive, Human | SCP | R21-14H | 20 UG |
¥52,000 |
p70S6K, Unactive, Human | SCP | R21-14H | 50 UG |
¥104,000 |
p70S6Kb, Active, Human | SCP | R22-10G | 5 UG |
¥54,000 |
p70S6Kb, Active, Human | SCP | R22-10G | 10 UG |
¥78,000 |
p70S6Kb, Unactive, Human | SCP | R22-14G | 20 UG |
¥52,000 |
p70S6Kb, Unactive, Human | SCP | R22-14G | 50 UG |
¥104,000 |
p70S6KL1, Human | SCP | R25-34G | 20 UG |
¥52,000 |
p70S6KL1, Human | SCP | R25-34G | 50 UG |
¥104,000 |
PDGF, Human | SCP | P841-40N | 10 UG |
販売終了 |
PDGF, Human | SCP | P841-40N | 50 UG |
販売終了 |
PDGFR α Mutant (D842V), Active, Human | SCP | P12-12BG | 5 UG |
¥54,000 |
PDGFR α Mutant (D842V), Active, Human | SCP | P12-12BG | 10 UG |
¥78,000 |
PDGFR α Mutant (T674I), Active, Human | SCP | P12-12CG | 5 UG |
¥54,000 |
PDGFR α Mutant (T674I), Active, Human | SCP | P12-12CG | 10 UG |
¥78,000 |
PDGFR α, Active, Mouse | SCP | P12-11G | 5 UG |
¥54,000 |
PDGFR α, Active, Mouse | SCP | P12-11G | 10 UG |
¥78,000 |
PDGFR α, Active, Human | SCP | P12-18G | 5 UG |
¥54,000 |
PDGFR α, Active, Human | SCP | P12-18G | 10 UG |
¥78,000 |
PDGFR β, Active, Human | SCP | P13-11G | 5 UG |
¥54,000 |
PDGFR β, Active, Human | SCP | P13-11G | 10 UG |
¥78,000 |
PDK1, Active, Human | SCP | P14-10H | 5 UG |
¥54,000 |
PDK1, Active, Human | SCP | P14-10H | 10 UG |
¥78,000 |
PDKtide, Human | SCP | P10-58 | 1 MG |
¥25,000 |
PHLPP2, Human | SCP | P72-21G | 20 UG |
¥52,000 |
PHLPP2, Human | SCP | P72-21G | 50 UG |
¥104,000 |
PI3K (p110 α(E545K)/p85 α) Mutant, Active, Human | SCP | P27-15H | 5 UG |
販売終了 |
PI3K (p110 α(E545K)/p85 α) Mutant, Active, Human | SCP | P27-15H | 10 UG |
販売終了 |
PI3K (p110α/p55γ), Active, Human | SCP | P27-10CH | 5 UG |
販売終了 |
PI3K (p110α/p55γ), Active, Human | SCP | P27-10CH | 10 UG |
販売終了 |
PI3K (p110 α/p85 α), Active, Human | SCP | P27-10H | 5 UG |
販売終了 |
PI3K (p110 α/p85 α), Active, Human | SCP | P27-10H | 10 UG |
販売終了 |
PI3K (p110 α/p85 α), Active, Human | SCP | P27-18H | 5 UG |
販売終了 |
PI3K (p110 α/p85 α), Active, Human | SCP | P27-18H | 10 UG |
販売終了 |
PI3K (p110 β/p85 α), Active, Human | SCP | P28-10H | 5 UG |
販売終了 |
PI3K (p110 β/p85 α), Active, Human | SCP | P28-10H | 10 UG |
販売終了 |
PI3K (p110 β/p85 β), Active, Human | SCP | P28-10BH | 5 UG |
販売終了 |
PI3K (p110 β/p85 β), Active, Human | SCP | P28-10BH | 10 UG |
販売終了 |
PI3K (p110 δ/p85 α), Active, Human | SCP | P30-10H | 5 UG |
販売終了 |
PI3K (p110 δ/p85 α), Active, Human | SCP | P30-10H | 10 UG |
販売終了 |
PI3K (p120 γ), Active, Human | SCP | P29-10H | 5 UG |
販売終了 |
PI3K (p120 γ), Active, Human | SCP | P29-10H | 10 UG |
販売終了 |
PI3K (p55 γ), Human | SCP | P31-30CH | 20 UG |
¥52,000 |
PI3K (p55 γ), Human | SCP | P31-30CH | 50 UG |
¥104,000 |
PI3K (p65 α), Human | SCP | P31-31H | 20 UG |
¥52,000 |
PI3K (p65 α), Human | SCP | P31-31H | 50 UG |
¥104,000 |
PI3K (p85 α), Human | SCP | P31-30H | 20 UG |
¥52,000 |
PI3K (p85 α), Human | SCP | P31-30H | 50 UG |
¥104,000 |
PI3K (p85 β), Human | SCP | P31-30BH | 20 UG |
¥52,000 |
PI3K (p85 β), Human | SCP | P31-30BH | 50 UG |
¥104,000 |
PI4K2A, Active, Human | SCP | P21-10G | 5 UG |
販売終了 |
PI4K2A, Active, Human | SCP | P21-10G | 10 UG |
販売終了 |
PI4K2B, Active, Human | SCP | P22-10G | 5 UG |
販売終了 |
PI4K2B, Active, Human | SCP | P22-10G | 10 UG |
販売終了 |
PI4KA, Human | SCP | P31-30G | 20 UG |
販売終了 |
PI4KA, Human | SCP | P31-30G | 50 UG |
販売終了 |
PI4KB, Active, Human | SCP | P32-10G | 5 UG |
販売終了 |
PI4KB, Active, Human | SCP | P32-10G | 10 UG |
販売終了 |
PIK3C2A, Active, Human | SCP | P23-11G | 5 UG |
販売終了 |
PIK3C2A, Active, Human | SCP | P23-11G | 10 UG |
販売終了 |
PIK3C2B, Human | SCP | P24-31BG | 20 UG |
販売終了 |
PIK3C2B, Human | SCP | P24-31BG | 50 UG |
販売終了 |
PIK3C2G, Active, Human | SCP | P25-11G | 5 UG |
販売終了 |
PIK3C2G, Active, Human | SCP | P25-11G | 10 UG |
販売終了 |
PIK3C3 (Vps34), Active, Human | SCP | P26-10G | 5 UG |
販売終了 |
PIK3C3 (Vps34), Active, Human | SCP | P26-10G | 10 UG |
販売終了 |
PIP4K2A, Active, Human | SCP | P76-10AG | 5 UG |
販売終了 |
PIP4K2A, Active, Human | SCP | P76-10AG | 10 UG |
販売終了 |
PIP4K2B, Human | SCP | P76-30BG | 20 UG |
販売終了 |
PIP4K2B, Human | SCP | P76-30BG | 50 UG |
販売終了 |
PIP4K2C, Active, Human | SCP | P76-10CG | 5 UG |
販売終了 |
PIP4K2C, Active, Human | SCP | P76-10CG | 10 UG |
販売終了 |
PIP5K1A, Active, Human | SCP | P16-10AG | 5 UG |
販売終了 |
PIP5K1A, Active, Human | SCP | P16-10AG | 10 UG |
販売終了 |
PIP5K1B, Active, Human | SCP | P16-10BG | 5 UG |
販売終了 |
PIP5K1B, Active, Human | SCP | P16-10BG | 10 UG |
販売終了 |
PIP5K1C, Active, Human | SCP | P16-10CG | 5 UG |
販売終了 |
PIP5K1C, Active, Human | SCP | P16-10CG | 10 UG |
販売終了 |
PIP5K3, Human | SCP | P17-31G | 20 UG |
¥52,000 |
PIP5K3, Human | SCP | P17-31G | 50 UG |
¥104,000 |
PTEN, Human | SCP | P23-34G | 20 UG |
¥52,000 |
PTEN, Human | SCP | P23-34G | 50 UG |
¥104,000 |
PTEN, Active, Human | SCP | P23-20G | 5 UG |
販売終了 |
PTEN, Active, Human | SCP | P23-20G | 10 UG |
販売終了 |
RGS1, Human | SCP | R39-30H | 20 UG |
¥52,000 |
RGS1, Human | SCP | R39-30H | 50 UG |
¥104,000 |
RON, Active, Human | SCP | M58-11G | 5 UG |
¥54,000 |
RON, Active, Human | SCP | M58-11G | 10 UG |
¥78,000 |
RSK4, Active, Human | SCP | R20-10G | 5 UG |
¥54,000 |
RSK4, Active, Human | SCP | R20-10G | 10 UG |
¥78,000 |
S6K Substrate, Human | SCP | S05-58 | 1 MG |
¥20,000 |
SDF-1 | SCP | S821-40N | 10 UG |
販売終了 |
SDF-1 | SCP | S821-40N | 50 UG |
販売終了 |
SGK1, Active, Human | SCP | S06-11G | 5 UG |
¥54,000 |
SGK1, Active, Human | SCP | S06-11G | 10 UG |
¥78,000 |
SGK1, Unactive, Human | SCP | S06-15G | 20 UG |
¥52,000 |
SGK1, Unactive, Human | SCP | S06-15G | 50 UG |
¥104,000 |
SGK2, Active, Human | SCP | S07-10G | 5 UG |
¥54,000 |
SGK2, Active, Human | SCP | S07-10G | 10 UG |
¥78,000 |
SGK2, Unactive, Human | SCP | S07-14G | 20 UG |
¥52,000 |
SGK2, Unactive, Human | SCP | S07-14G | 50 UG |
¥104,000 |
SGK3, Active, Human | SCP | S08-10G | 5 UG |
¥54,000 |
SGK3, Active, Human | SCP | S08-10G | 10 UG |
¥78,000 |
SGK3, Unactive, Human | SCP | S08-14G | 20 UG |
¥52,000 |
SGK3, Unactive, Human | SCP | S08-14G | 50 UG |
¥104,000 |
SGKtide | SCP | S08-58 | 1 MG |
¥20,000 |
SMAD1, Human | SCP | S10-30G | 20 UG |
¥52,000 |
SMAD1, Human | SCP | S10-30G | 50 UG |
¥104,000 |
SMAD2, Human | SCP | S11-30G | 20 UG |
¥52,000 |
SMAD2, Human | SCP | S11-30G | 50 UG |
¥104,000 |
SMAD3, Human | SCP | S12-30G | 20 UG |
¥52,000 |
SMAD3, Human | SCP | S12-30G | 50 UG |
¥104,000 |
SMAD4, Human | SCP | S13-30G | 20 UG |
¥52,000 |
SMAD4, Human | SCP | S13-30G | 50 UG |
¥104,000 |
SMAD5, Human | SCP | S14-30G | 20 UG |
¥52,000 |
SMAD5, Human | SCP | S14-30G | 50 UG |
¥104,000 |
SMAD9, Human | SCP | S17-30G | 20 UG |
¥52,000 |
SMAD9, Human | SCP | S17-30G | 50 UG |
¥104,000 |
STK3, Active, Human | SCP | S24-10G | 5 UG |
¥54,000 |
STK3, Active, Human | SCP | S24-10G | 10 UG |
¥78,000 |
SYK, Active, Human | SCP | S52-10G | 5 UG |
¥54,000 |
SYK, Active, Human | SCP | S52-10G | 10 UG |
¥78,000 |
TAK1-TAB1, Active, Human | SCP | M15-13G | 5 UG |
¥54,000 |
TAK1-TAB1, Active, Human | SCP | M15-13G | 10 UG |
¥78,000 |
TGFB1, Human | SCP | T831-40N | 10 UG |
¥49,000 |
TGFB1, Human | SCP | T831-40N | 50 UG |
¥78,000 |
TGFB3, Human | SCP | T833-40CN | 10 UG |
販売終了 |
TGFB3, Human | SCP | T833-40CN | 50 UG |
販売終了 |
TGFBR1 (ALK5), Active, Human | SCP | T07-11G | 5 UG |
¥54,000 |
TGFBR1 (ALK5), Active, Human | SCP | T07-11G | 10 UG |
¥78,000 |
TGFBR1 Peptide, Human | SCP | T36-58 | 1 MG |
¥20,000 |
TGFBR1, Unactive, Human | SCP | T07-35G | 20 UG |
¥52,000 |
TGFBR1, Unactive, Human | SCP | T07-35G | 50 UG |
¥104,000 |
TGFBR2, Active, Human | SCP | T08-11G | 5 UG |
¥54,000 |
TGFBR2, Active, Human | SCP | T08-11G | 10 UG |
¥78,000 |
TNF-α, Human | SCP | T860-40N | 10 UG |
販売終了 |
TNF-α, Human | SCP | T860-40N | 50 UG |
販売終了 |
TNFB, Human | SCP | T861-40N | 10 UG |
販売終了 |
TNFB, Human | SCP | T861-40N | 50 UG |
販売終了 |
TRAIL, Human | SCP | T880-40N | 10 UG |
販売終了 |
TRAIL, Human | SCP | T880-40N | 50 UG |
販売終了 |
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用としては使用しないように、十分ご注意ください。
※ 表示価格について
- 「高精製度キナーゼ ‐ AKT/PKB Pathway」は、下記のカテゴリーに属しています。
-
- カテゴリから探す > シグナル伝達 > リン酸化/ユビキチン化/SUMO化 > プロテインキナーゼ
- 研究分野から探す > がん研究 > リン酸化の検出・測定 > リコンビナントキナーゼ