記事ID ： 14486

発生や癌の研究に！ Smoothened agonist／ligand SAG

メーカー名：Enzo Life Sciences,Inc.

SAG は、Smo（Smoothened）の heptahelical ドメインに作用することで、Smo とその下流のエフェクターのカップリングを制御する細胞透過性のベンゾチオフェン化合物です（KD = 59 nM）。

Hedgehog パスウェイを活性化し［EC50 = ～3 nM （NIH 3T3 由来 Shh-LIGHT2 細胞）］、また、Cyclopamine（品番： BML-GR334）による Smo の阻害を中和する働きが知られています。低い濃度では活性化因子として、非常に高い濃度では阻害剤として作用することが報告されています。

仕様

SAG

化学式	C₂₈H₂₈ClN₃OS
分子量	490.1
CAS RN®	364590-63-6
純度	≥95% (HR-MS, ¹H-NMR, ¹³C-NMR)
外観	白-灰白色固体
溶解性	DMSO（10mg/mL）に可溶水に難溶（HCl を加えて酸性化することで水溶性が向上）

ZytoLight® FISH Dual Color Probe

2色（緑・オレンジ）

［商品詳細］

ZytoLight® SPEC CD274, PDCD1LG2 / CEN 9 Dual Color Probe
- 癌研究に！ CD274、PDCD1LG2 遺伝子クラスターの増幅を検出するFISHプローブ
ZytoLight® BRAF プローブ
- 癌研究に！ BRAF 遺伝子の再配列／増幅を検出

品名	メーカー	品番	包装	希望販売価格
ZytoLight^(R) SPEC 1p36/1q25 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2075-50	50 UL [5 test]	￥84,000
ZytoLight^(R) SPEC 1p36/1q25 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2075-200	200 UL [20 test]	￥281,000
ZytoLight^(R) SPEC FOXO1/PAX7 Dual Color Single Fusion Probe, ZyOrange/ZyGreen	ZYV	Z-2019-50	50 UL [5 test]	￥80,000
ZytoLight^(R) SPEC FOXO1/PAX7 Dual Color Single Fusion Probe, ZyOrange/ZyGreen	ZYV	Z-2019-200	200 UL [20 test]	￥268,000
ZytoLight SPEC MCL1/1p12 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2173-200	200 UL [20 test]	￥272,000
ZytoLight^(R) SPEC NTRK1 Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2167-200	200 UL [20 test]	￥278,000
ZytoLight SPEC ABL2 Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2200-50	50 UL [5 test]	￥77,000
ZytoLight^(R) SPEC MDM4/1p12 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2080-200	200 UL [20 test]	￥281,000
ZytoLight^(R) SPEC MYCN/2q11 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2074-50	50 UL [5 tests]	￥84,000
ZytoLight^(R) SPEC MYCN/2q11 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2074-200	200 UL [20 test]	￥281,000
ZytoLight^(R) SPEC ALK Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2124-50	50 UL [5 test]	￥74,000
ZytoLight^(R) SPEC ALK Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2124-200	200 UL [20 test]	￥246,000
ZytoLight SPEC ALK/2q11 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2161-200	200 UL [20 test]	￥288,000
ZytoLight^(R) SPEC EML4 Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2136-50	50 UL [5 test]	￥84,000
ZytoLight SPEC MERTK/2q11 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2155-200	200 UL [20 test]	販売終了
ZytoLight^(R) SPEC ERBB4/2q11 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2057-200	200 UL [20 test]	￥292,000
ZytoLight^(R) SPEC FOXO1/PAX3 Dual Color Single Fusion Probe, ZyOrange/ZyGreen	ZYV	Z-2018-50	50 UL [5 test]	￥80,000
ZytoLight^(R) SPEC FOXO1/PAX3 Dual Color Single Fusion Probe, ZyOrange/ZyGreen	ZYV	Z-2018-200	200 UL [20 test]	￥268,000
ZytoLight^(R) SPEC VHL/CEN 3 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2084-200	200 UL [20 test]	￥292,000
ZytoLight^(R) SPEC FHIT/CEN 3 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2062-200	200 UL [20 test]	￥292,000
ZytoLight^(R) SPEC TFG Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2133-50	50 UL [5 test]	販売終了
ZytoLight^(R) SPEC WWTR1 Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2212-50	50 UL [5 tests]	￥69,000
ZytoLight^(R) SPEC PIK3CA/CEN 3 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2140-200	200 UL [20 test]	￥281,000
ZytoLight^(R) SPEC SOX2/CEN 3 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2127-200	200 UL [20 test]	￥281,000
ZytoLight SPEC BCL6 Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2177-50	50 UL [5 test]	￥73,000
ZytoLight^(R) SPEC BCL6 Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2177-200	200 UL [20 test]	￥244,000
ZytoLight SPEC FGFR3 Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2170-50	50 UL [5 test]	￥79,000
ZytoLight^(R) SPEC FGFR3 Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2170-200	200 UL [20 test]	￥264,000
ZytoLight^(R) SPEC FGFR3/4p11 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2082-200	200 UL [20 test]	￥281,000
ZytoLight SPEC TERT/5q31 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2091-50	50 UL [5 test]	￥77,000
ZytoLight^(R) SPEC EGR1/5p15 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2107-50	50 UL [5 tests]	販売終了
ZytoLight^(R) SPEC EGR1/5p15 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2107-200	200 UL [20 test]	販売終了
ZytoLight^(R) SPEC EGR1/D5S23,D5S721 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2211-50	50 UL [5 tests]	￥66,000
ZytoLight ^(R) SPEC CSF1R/D5S23,D5S721 Dual Color Probe	ZYV	Z-2268-50	5 TEST [50 UL]	￥69,000
ZytoLight SPEC CSF1R Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2202-50	50 UL [5 test]	￥77,000
ZytoLight SPEC PDGFRB Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2197-50	50 UL [5 test]	￥73,000
ZytoLight^(R) SPEC IRF4,DUSP22 Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2210-50	50 UL [5 tests]	￥72,000
ZytoLight SPEC VEGFA/CEN 6 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2195-200	0.2 ML [20 test]	￥289,000
ZytoLight^(R) SPEC ROS1 Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2144-50	50 UL [5 test]	￥84,000
ZytoLight^(R) SPEC ROS1 Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2144-200	200 UL [20 test]	￥281,000
ZytoLight SPEC ROS1/CEN 6 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2162-200	200 UL [20 test]	￥288,000
ZytoLight^(R) SPEC MYB Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2143-200	200 UL [20 test]	￥267,000
ZytoLight^(R) SPEC ESR1/CEN 6 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2069-50	50 UL [5 test]	￥88,000
ZytoLight^(R) SPEC ESR1/CEN 6 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2069-200	200 UL [20 test]	￥292,000
ZytoLight^(R) SPEC ETV1/CEN 7 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2141-200	200 UL [20 test]	販売終了
ZytoLight^(R) SPEC JAZF1 Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2132-50	50 UL [5 test]	￥80,000
ZytoLight^(R) SPEC EGFR/CEN 7 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2033-50	50 UL [5 test]	￥88,000
ZytoLight^(R) SPEC EGFR/CEN 7 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2033-200	200 UL [20 test]	￥292,000
ZytoLight^(R) SPEC MET/CEN 7 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2087-200	200 UL [20 test]	￥281,000
ZytoLight SPEC BRAF Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2189-200	0.2 ML [20 test]	￥278,000
ZytoLight SPEC BRAF/CEN 7 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2191-200	0.2 ML [20 test]	￥292,000
ZytoLight^(R) SPEC NRG1 Dual Colour Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2181-200	200 UL [20 test]	￥278,000
ZytoLight SPEC FGFR1 Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2168-50	50 UL [5 test]	￥79,000
ZytoLight^(R) SPEC FGFR1 Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2168-200	200 UL [20 test]	￥264,000
ZytoLight^(R) SPEC FGFR1/CEN 8 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2072-50	50 UL [5 test]	￥88,000
ZytoLight^(R) SPEC FGFR1/CEN 8 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2072-200	200 UL [20 test]	￥292,000
ZytoLight SPEC RUNX1/RUNX1T1 Dual Color Dual Fusion Probe, ZyOrange/ZyGreen	ZYV	Z-2112-50	50 UL [5 test]	￥73,000
ZytoLight^(R) SPEC MYC Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2090-50	50 UL [5 test]	￥70,000
ZytoLight^(R) SPEC MYC Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2090-200	200 UL [20 test]	￥233,000
ZytoLight SPEC MYC/CEN 8 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2092-50	50 UL [5 test]	￥68,000
ZytoLight^(R) SPEC MYC/CEN 8 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2092-200	200 UL [20 test]	￥226,000
ZytoLight SPEC MYC/IGH Dual Color Dual Fusion Probe, ZyOrange/ZyGreen	ZYV	Z-2105-50	50 UL [5 test]	￥66,000
ZytoLight^(R) SPEC MYC/IGH Dual Color Dual Fusion Probe, ZyOrange/ZyGreen	ZYV	Z-2105-200	200 UL [20 test]	￥220,000
ZytoLight^(R) SPEC CD274,PDCD1LG2/CEN 9 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2179-50	50 UL [5 tests]	￥82,000
ZytoLight^(R) SPEC CD274,PDCD1LG2/CEN 9 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2179-200	0.2 ML [20 test]	￥272,000
ZytoLight SPEC CDKN2A/CEN 9 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2063-50	50 UL [5 test]	￥85,000
ZytoLight^(R) SPEC CDKN2A/CEN 9 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2063-200	200 UL [20 test]	￥282,000
ZytoLight SPEC NTRK2 Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2205-200	200 UL [20 test]	￥278,000
ZytoLight^(R) SPEC NR4A3 Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2145-50	50 UL [5 test]	￥84,000
ZytoLight SPEC ABL1 Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2199-50	50 UL [5 test]	￥77,000
ZytoLight^(R) SPEC BCR/ABL1 Dual Color Dual Fusion Probe, ZyOrange/ZyGreen	ZYV	Z-2111-50	50 UL [5 test]	￥73,000
ZytoLight^(R) SPEC BCR/ABL1 Dual Color Dual Fusion Probe, ZyOrange/ZyGreen	ZYV	Z-2111-200	200 UL [20 test]	￥244,000
ZytoLight^(R) SPEC KIF5B Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2131-50	50 UL [5 test]	￥84,000
ZytoLight^(R) SPEC RET Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2148-50	50 UL [5 test]	￥84,000
ZytoLight^(R) SPEC RET Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2148-200	200 UL [20 test]	￥281,000
ZytoLight^(R) SPEC PTEN/CEN 10 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2078-50	50 UL [5 tests]	￥72,000
ZytoLight^(R) SPEC PTEN/CEN 10 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2078-200	200 UL [20 test]	￥239,000
ZytoLight^(R) SPEC FGFR2 Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2169-200	200 UL [20 test]	￥278,000
ZytoLight^(R) SPEC FGFR2/CEN 10 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2122-200	200 UL [20 test]	￥281,000
ZytoLight^(R) SPEC CARS Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2137-50	50 UL [5 test]	￥80,000
ZytoLight^(R) SPEC WT1 Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2142-50	50 UL [5 test]	￥80,000
ZytoLight SPEC CCND1 Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2108-50	50 UL [5 test]	￥70,000
ZytoLight^(R) SPEC CCND1 Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2108-200	200 UL [20 test]	￥233,000
ZytoLight SPEC CCND1/CEN 11 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2071-50	50 UL [5 test]	￥66,000
ZytoLight^(R) SPEC CCND1/CEN 11 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2071-200	200 UL [20 test]	￥220,000
ZytoLight SPEC CCND1/IGH Dual Color Dual Fusion Probe, ZyOrange/ZyGreen	ZYV	Z-2125-50	50 UL [5 test]	￥66,000
ZytoLight^(R) SPEC CCND1/IGH Dual Color Dual Fusion Probe, ZyOrange/ZyGreen	ZYV	Z-2125-200	200 UL [20 test]	￥220,000
ZytoLight^(R) SPEC FGF3,4,19/CEN 11 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2158-200	200 UL [20 test]	販売終了
ZytoLight^(R) SPEC MAML2 Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2014-50	50 UL [5 tests]	￥80,000
ZytoLight^(R) SPEC MAML2 Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2014-200	200 UL [20 test]	￥268,000
ZytoLight SPEC BIRC3/MALT1 Dual Color Dual Fusion Probe, ZyOrange/ZyGreen	ZYV	Z-2146-50	50 UL [5 test]	￥73,000
ZytoLight^(R) SPEC BIRC3/MALT1 Dual Color Dual Fusion Probe, ZyOrange/ZyGreen	ZYV	Z-2146-200	200 UL [20 test]	￥244,000
ZytoLight SPEC TP53/ATM Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2159-50	50 UL [5 test]	￥74,000
ZytoLight SPEC TP53/ATM Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2159-200	200 UL [20 test]	￥246,000
ZytoLight SPEC KMT2A Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2193-50	50 UL [5 test]	￥73,000
ZytoLight SPEC ETV6 Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2176-50	50 UL [5 test]	￥73,000
ZytoLight^(R) SPEC ETV6 Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2176-200	200 UL [20 test]	￥244,000
ZytoLight SPEC ETV6/RUNX1 Dual Color Dual Fusion Probe, ZyOrange/ZyGreen	ZYV	Z-2157-50	50 UL [5 test]	￥70,000
ZytoLight^(R) SPEC KRAS/CEN 12 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2115-200	200 UL [20 test]	￥281,000
ZytoLight^(R) SPEC ERBB3/CEN 12 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2056-200	200 UL [20 test]	￥292,000
ZytoLight^(R) SPEC DDIT3 Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2100-50	50 UL [5 test]	￥66,000
ZytoLight SPEC DDIT3 Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2100-200	200 UL [20 test]	￥220,000
ZytoLight SPEC CDK4/CEN 12 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2103-50	50 UL [5 test]	￥84,000
ZytoLight^(R) SPEC CDK4/CEN 12 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2103-200	200 UL [20 test]	￥281,000
ZytoLight^(R) SPEC MDM2/CEN 12 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2013-50	50 UL [5 test]	￥88,000
ZytoLight^(R) SPEC MDM2/CEN 12 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2013-200	200 UL [20 test]	￥292,000
ZytoLight^(R) SPEC 13/21 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2164-200	200 UL [20 test]	￥142,000
ZytoLight^(R) SPEC FOXO1 Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2139-50	50 UL [5 test]	￥76,000
ZytoLight SPEC RB1/13q12 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2165-50	50 UL [5 test]	販売終了
ZytoLight SPEC RB1/13q12 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2165-200	200 UL [20 test]	販売終了
ZytoLight SPEC GAS6/13q12 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2156-200	0.2 ML [20 test]	販売終了
ZytoLight SPEC BCL2L2/14q32 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2172-200	200 UL [20 test]	販売終了
ZytoLight^(R) SPEC IGH Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2110-50	50 UL [5 test]	￥66,000
ZytoLight^(R) SPEC IGH Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2110-200	200 UL [20 test]	￥220,000
ZytoLight SPEC BCL2/IGH Dual Color Dual Fusion Probe, ZyOrange/ZyGreen	ZYV	Z-2114-50	50 UL [5 test]	￥66,000
ZytoLight^(R) SPEC BCL2/IGH Dual Color Dual Fusion Probe, ZyOrange/ZyGreen	ZYV	Z-2114-200	200 UL [20 test]	￥220,000
ZytoLight SPEC NUTM1 Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2208-200	200 UL [20 test]	￥278,000
ZytoLight^(R) SPEC PML/RARA Dual Color Dual Fusion Probe, ZyOrange/ZyGreen	ZYV	Z-2113-50	50 UL [5 tests]	￥73,000
ZytoLight^(R) SPEC PML/RARA Dual Color Dual Fusion Probe, ZyOrange/ZyGreen	ZYV	Z-2113-200	200 UL [20 test]	￥233,000
ZytoLight SPEC NTRK3 Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2206-200	200 UL [20 test]	￥278,000
ZytoLight^(R) SPEC FUS Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2130-50	50 UL [5 test]	￥66,000
ZytoLight^(R) SPEC CBFB Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2207-50	50 UL [5 tests]	￥72,000
ZytoLight SPEC TP53/17q22 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2198-50	50 UL [5 test]	￥77,000
ZytoLight SPEC TP53/CEN 17 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2153-50	50 UL [5 test]	￥75,000
ZytoLight^(R) SPEC TP53/CEN 17 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2153-200	200 UL [20 test]	￥258,000
ZytoLight^(R) SPEC USP6 Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2151-50	50 UL [5 test]	￥84,000
ZytoLight^(R) SPEC ERBB2/CEN 17 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2015-50	50 UL [5 test]	￥88,000
ZytoLight^(R) SPEC ERBB2/CEN 17 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2015-200	200 UL [20 test]	￥292,000
ZytoLight^(R) SPEC ERBB2/CEN 17 Dual Color Probe Kit, ZyOrange/ZyGreen	ZYV	Z-2020-5	5 TEST	￥101,000
ZytoLight^(R) SPEC ERBB2/CEN 17 Dual Color Probe Kit, ZyOrange/ZyGreen	ZYV	Z-2020-20	20 TEST	￥336,000
ZytoLight CEN 17/SPEC ERBB2 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2077-50	0.05 ML [5 test]	￥84,000
ZytoLight CEN 17/SPEC ERBB2 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2077-200	0.2 ML [20 test]	￥281,000
ZytoLight^(R) SPEC ERBB2/D17S122 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2190-50	0.05 ML [5 test]	￥88,000
ZytoLight^(R) SPEC COL1A1 Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2121-200	200 UL [20 test]	￥249,000
ZytoLight^(R) SPEC COL1A1/PDGFB Dual Color Dual Fusion Probe, ZyOrange/ZyGreen	ZYV	Z-2116-50	50 UL [5 test]	￥80,000
ZytoLight^(R) SPEC COL1A1/PDGFB Dual Color Dual Fusion Probe, ZyOrange/ZyGreen	ZYV	Z-2116-200	200 UL [20 test]	￥267,000
ZytoLight^(R) SPEC TYMS/CEN 18 Dual Color Probe (ZyGreen/ZyOrange), ZyOrange/ZyGreen	ZYV	Z-2098-200	200 UL [20 test]	販売終了
ZytoLight^(R) SPEC SS18 Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2097-50	50 UL [5 test]	￥66,000
ZytoLight SPEC SS18 Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2097-200	200 UL [20 test]	￥220,000
ZytoLight SPEC BCL2 Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2192-50	50 UL [5 test]	￥70,000
ZytoLight^(R) SPEC BCL2 Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2192-200	0.2 ML [20 test]	￥233,000
ZytoLight SPEC BCL2/CEN 18 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2174-50	50 UL [5 test]	￥79,000
ZytoLight SPEC MALT1 Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2196-50	50 UL [5 test]	￥70,000
ZytoLight SPEC MALT1 Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2196-200	200 UL [20 test]	￥233,000
ZytoLight^(R) SPEC 19q13/19p13 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2076-50	50 UL [5 test]	￥84,000
ZytoLight^TM SPEC 19q13/19p13 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2076-200	200 UL [20 test]	￥281,000
ZytoLight SPEC AXL/19p13 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2154-200	200 UL [20 test]	販売終了
ZytoLight SPEC BCL2L1/CEN 20 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2171-200	200 UL [20 test]	￥272,000
ZytoLight^(R) SPEC PTPRT/20q11 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2213-50	50 UL [5 tests]	￥66,000
ZytoLight^(R) SPEC ERG Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2138-200	200 UL [20 test]	￥281,000
ZytoLight^(R) SPEC SMARCB1/22q12 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2178-50	0.05 ML [5 test]	￥82,000
ZytoLight^(R) SPEC EWSR1 Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2096-50	50 UL [5 test]	￥66,000
ZytoLight SPEC EWSR1 Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2096-200	200 UL [20 test]	￥220,000
ZytoLight SPEC PDGFB Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2119-50	50 UL [5 test]	￥76,000
ZytoLight SPEC PDGFB Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2119-200	20 TEST [200 μl]	￥255,000
ZytoLight SPEC CRLF2 Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2201-50	50 UL [5 test]	￥77,000
ZytoLight SPEC TFE3 Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2109-50	50 UL [5 test]	￥76,000
ZytoLight^(R) SPEC TFE3 Dual Color Break Apart Probe, ZyOrange/ZyGreen	ZYV	Z-2109-200	200 UL [20 test]	￥255,000
ZytoLight^(R) SPEC MAF/IGH Dual Color Dual Fusion Probe, ZyOrange/ZyGreen	ZYV	Z-2270-50	50 UL [5 tests]	￥66,000
ZytoLight^(R) SPEC MAFB/IGH Dual Color Dual Fusion Probe, ZyOrange/ZyGreen	ZYV	Z-2271-50	50 UL [5 tests]	￥66,000
ZytoLight^(R) CEN X/Yq12 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2016-50	50 UL [5 test]	￥43,000
ZytoLight^(R) CEN X/Yq12 Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2016-200	200 UL [20 test]	￥142,000
ZytoLight^(R) CEN X/Y Dual Color Probe, ZyOrange/ZyGreen	ZYV	Z-2120-200	200 UL [20 test]	￥142,000

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ZytoLight® FISH Triple Color Probe

3色（緑・青・オレンジ）

品名	メーカー	品番	包装	希望販売価格
ZytoLight^(R) SPEC RREB1/MYB/CEN 6 Triple Color Probe, ZyOrange/ZyGreen/ZyBlue	ZYV	Z-2152-50	50 UL [5 tests]	￥122,000
ZytoLight SPEC RREB1/MYB/CEN 6 Triple Color Probe, ZyGreen/ZyOrange/ZyBlue	ZYV	Z-2152-200	200 UL [20 test]	お問い合わせ
ZytoLight^(R) SPEC 11q gain/loss Triple Color Probe, ZyOrange/ZyGreen/ZyBlue	ZYV	Z-2216-50	50 UL [5 tests]	￥76,000
ZytoLight^(R) SPEC 13/CEN 18/SPEC 21 Triple Color Probe, ZyGreen/ZyOrange/ZyBlue	ZYV	Z-2095-50	50 UL [5 test]	￥84,000
ZytoLight^(R) SPEC 13/CEN 18/SPEC 21 Triple Color Probe, ZyGreen/ZyOrange/ZyBlue	ZYV	Z-2095-200	200 UL [20 test]	￥281,000
ZytoLight SPEC D13S319/13q34/CEN 12 Triple Color Probe, ZyOrange/ZyBlue/ZyGreen	ZYV	Z-2160-50	50 UL [5 test]	￥107,000
ZytoLight SPEC D13S319/13q34/CEN 12 Triple Color Probe, ZyOrange/ZyBlue/ZyGreen	ZYV	Z-2160-200	200 UL [20 test]	￥357,000
ZytoLight^(R) SPEC ERBB2/TOP2A/CEN 17 Triple Color Probe, ZyGreen/ZyOrange/ZyBlue	ZYV	Z-2093-50	50 UL [5 test]	￥135,000
ZytoLight^(R) SPEC HER2/TOP2A/CEN 17 Triple Color Probe, ZyGreen/ZyOrange/ZyBlue	ZYV	Z-2093-200	200 UL [20 test]	お問い合わせ
ZytoLight SPEC 18/CEN X/Y Triple Color Probe, ZyOrange/ZyGreen/ZyBlue	ZYV	Z-2163-200	200 UL [20 test]	￥259,000
ZytoLight^(R) SPEC 21/CEN X/Yq12 Triple Color Probe, ZyOrange/ZyGreen/ZyBlue	ZYV	Z-2180-200	200 UL [20 test]	￥246,000

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ZytoLight® FISH Quadruple Color Probe

4色（ゴールド・赤・緑・青）

［商品詳細］

ZytoLight® SPEC p16/CEN 3/7/17 Quadruple Color Probe
- 世界初！FISH用4カラープローブ

品名	メーカー	品番	包装	希望販売価格
ZytoLight^(R) SPEC VHL/1p12/CEN 7/17 Quadruple Color Probe, ZyGreen/ZyRed/ZyBlue/ZyGold	ZYV	Z-2102-200	200 UL [20 test]	お問い合わせ
ZytoLight^(R) SPEC CCND1 Break Apart/2q11/CEN 6 Quadruple Color Probe, ZyGreen/ZyRed/ZyBlue/ZyGold	ZYV	Z-2118-200	200 UL [20 test]	お問い合わせ
ZytoLight^(R) SPEC CDKN2A/CEN 3/7/17 Quadruple Color Probe, ZyGold/ZyRed/ZyGreen/ZyBlue	ZYV	Z-2081-50	50 UL [5 test]	￥211,000
ZytoLight^(R) SPEC CDKN2A/CEN 3/7/17 Quadruple Color Probe, ZyGold/ZyRed/ZyGreen/ZyBlue	ZYV	Z-2081-200	200 UL [20 test]	お問い合わせ
ZytoLight SPEC FGFR3 Break Apart/FGFR2/FGFR1 Quadruple Color Probe, ZyGreen/ZyRed/ZyBlue/ZyGold	ZYV	Z-2186-200	200 UL [20 test]	販売終了
ZytoLight SPEC MYC/CDKN2A/ERBB2/ZNF217 Quadruple Color Probe, ZyBlue/ZyRed/ZyGreen/ZyGold	ZYV	Z-2204-200	200 UL [20 test]	販売終了

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【関連商品】

ZytoLight® FISH Implementation Kit
- 蛍光 in situ ハイブリダイゼーション用の試薬セット
ZytoLight® SPEC ALK/EML4 TriCheck™ Probe
- ALK-EML4転位の検出に最適なFISHプローブ

製品使用文献

Functional anterior pituitary generated in self-organizing culture of human embryonic stem cells: C. Ozone, et al.; Nat. Commun. 7, Article number 10351 (2016), Application(s): Cell culture, Abstract ;
Identification and Correction of Mechanisms Underlying Inherited Blindness in Human iPSC-Derived Optic Cups: D.A. Parfitt, et al.; Cell Stem Cell 18, 769 (2016), Application(s): Cell culture, Abstract ;
Sequential Differentiation of Embryonic Stem Cells into Neural Epithelial-Like Stem Cells and Oligodendrocyte Progenitor Cells: J. Bian, et al.; PLoS One 11, e0155227 (2016), Application(s): Cell culture, Abstract ; Full Text
Modeling amyotrophic lateral sclerosis in pure human iPSc-derived motor neurons isolated by a novel FACS double selection technique: D. Toli, et al.; Neurobiol. Dis. 82, 269 (2015), Application(s): Cell Culture, Abstract ;
Subregional specification of embryonic stem cell-derived ventral telencephalic tissues by timed and combinatory treatment with extrinsic signals: T. Danjo, et al.; J. Neurosci. 31, 1919 (2011), Abstract ;
Identification of a suppressive mechanism for Hedgehog signaling through a novel interaction of Gli with 14-3-3: Y. Asoaka, et al.; J. Biol. Chem. 285, 4185 (2010), Abstract ; Full Text
Wnt signaling stimulates transcriptional outcome of the Hedgehog pathway by stabilizing GLI1 mRNA: F.K. Noubissi, et al.; Cancer Res. 69, 8572 (2009), Abstract ; Full Text
Oxysterols stimulate Sonic hedgehog signal transduction and proliferation of medulloblastoma cells: R.B. Corcoran and M.P. Scott; PNAS 103, 8408 (2006), Abstract ; Full Text
Smoothened Signal Transduction is Promoted by G-Protein Coupled Receptor Kinase 2: A.R. Meloni et al.; Mol Cell Biol. 26, 7550 (2006), Abstract ;
Activity-dependent internalization of smoothened mediated by beta-arrestin 2 and GRK2: W. Chen, et al.; Science 306, 2257 (2004), Abstract ;
Small molecule modulation of Smoothened activity: J.K. Chen, et al.; PNAS 99, 14071 (2002), Abstract ; Full Text
Small-molecule modulators of Hedgehog signaling: identification and characterization of Smoothened agonists and antagonists: M. Frank-Kamenetsky, et al.; J. Biol. 1, 10 (2002), Abstract ; Full Text