Anti dimethyl Histone H3, dimethyl Lys27 - Cosmo Bio Co.,Ltd.



Anti dimethyl Histone H3, dimethyl Lys27 Antibody

Catalog No.: MCA-MABI0324-100-EX
Size: 100UL
[1 mg/ml]
Price: ¥26000
antigen/source: dimethyl Histone H3, dimethyl Lys27
host: Mouse
Label: Unlabeled
Application: Chromatin Immunoprecipitation
Immuno Blot
Immunocytochemistry (cell)
Storage: -20C
Immunogen: Human
Isotype: IgG2a
Clone: MABI0324
Reacts with: Human


Histones are the main protein components of chromatin. To facilitate nuclear packaging and control of gene expression, DNA in chromatin is wound around nucleosome particles composed primarily of the Histones H2A, H2B, H3, and H4. Histone N-terminal regions (histone tails) protrude from the nucleosome core and are subject to a variety of reversible, regulated modifications (including acetlylation, phosphorylation, and methylation) influencing transcription and chromatin structure. How such modifications are regulated and how these modifications effect gene expression continues to be an area of intense interest and research. In such studies, chromatin immunoprecipitation (ChIP) is perhaps the most widely used experimental procedure. Due to the inherent variability and limited supply of polyclonal antibodies, well characterized monoclonal antibodies are preferred reagents for ChIP.
The versitile set of anti-histone monoclonal antibodies offered here are therefore highly valuable reagents to your lab's epigenetic toolbox.