MART-1(別名Melan A)はメラノサイトの分化抗原です1-2。MART-1は正常皮膚のメラノサイト、網膜、母斑、およびほとんどのメラノーマに存在する膜貫通型タンパク質です。MART-1は転移性メラノーマを特定するための優れたマーカーです3-11。
仕様
反応性 | パラフィン切片 |
---|---|
染色箇所 | 細胞質 |
コントロール | メラノーマ |
希釈率(濃縮タイプ用) | 1:100-1:500 |
Clone | M2-7C10 |
商品情報
参考文献
- Kawakam Y, et al. Cloning of the gene coding for a shared human melanoma antigen recognized by autologous T cells infiltrating into tumor. Proc. Natl. Acad. Sci. U S A. 1994; 91: 3515-19.
- Couli PG, et al. A new gene coding for a differentiation antigen recognized by autologous cytolytic T lymphocytes on HLA-A2 melanomas. J Exp Med. 1994; 180: 35-42.
- Kageshita T, et al. Differential expression of MART-1 in primary and metastatic melanoma lesions. J Immunother. 1997; 20:460-5.
- Fetsch PA, et al. Melanoma-associated antigen recognized by T cells (MART-1): the advent of a preferred immunocytochemical antibody for the diagnosis of metastatic malignant melanoma with fine-needle aspiration. Cancer. 1999; 87:37-42.
- Bergman R, et al. A comparative immunohistochemical study of MART-1 expression in Spitz nevi, ordinary melanocytic nevi, and malignant melanomas. J Am Acad Dermatol. 2000; 42:496-500.
- Orosz Z. Melan-A/Mart-1 expression in various melanocytic lesions and in non-melanocytic soft tissue tumours. Histopathology. 1999; 34:517-25.
- Yaziji H, et al. Immunohistochemical markers of melanocytic tumors. Int J Surg Pathol. 2003; 11:11-5.
- Suchak R, et al. Evaluation of the role of routine melan-A immunohistochemistry for exclusion of microinvasion in 120 cases of lentigo maligna. Am J Dermatopathol. 2014; 36:387-91.
- Helm K et al. Immunohistochemistry of pigmented actinic keratoses, actinic keratoses, melanomas in situ and solar lentigines with Melan-A. J Cutan Pathol. 2008; 35:931-4.
- Kucher C, et al. Expression of Melan-A and Ki-67 in desmoplastic melanoma and desmoplastic nevi. Am J Dermatopathol. 2004; 26:452-7.
- Nielsen PS, et al. Immunohistochemical double stains against Ki67/MART1 and HMB45/MITF: promising diagnostic tools in melanocytic lesions. Am J Dermatopathol. 2011; 33:361-70.
【濃縮タイプ】MART-1 (Melan A) (M2-7C10) マウスモノクローナル抗体
品名 | メーカー | 品番 | 包装 | 希望販売価格 |
---|---|---|---|---|
Anti MART-1 (Melan A), Human (Mouse) Unlabeled, M2-7C10 | CMC | 281M-94-RUO | 0.1 ML |
¥35,000 |
Anti MART-1 (Melan A), Human (Mouse) Unlabeled, M2-7C10 | CMC | 281M-96-RUO | 1 ML |
¥136,000 |
【希釈済】MART-1 (Melan A) (M2-7C10) マウスモノクローナル抗体
品名 | メーカー | 品番 | 包装 | 希望販売価格 |
---|---|---|---|---|
Anti MART-1 (Melan A), (Mouse) , M2-7C10 | CMC | 281M-90-RUO | 25 ML |
¥269,000 |
Anti MART-1 (Melan A), Human (Mouse) Unlabeled, M2-7C10 | CMC | 281M-97-RUO | 1 ML |
¥27,000 |
Anti MART-1 (Melan A), Human (Mouse) Unlabeled, M2-7C10 | CMC | 281M-98-RUO | 7 ML |
¥87,000 |
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