ヒト、マウス、ラット、ウサギなど動物種毎に最適密度に調製済み！！ Lympholyte® リンパ球 (PBMC) / Lympholyte®-poly 顆粒球 分離溶液

Lympholyte®-M

1. Sun Y, et al. (2023) Targeting TBK1 to overcome resistance to cancer immunotherapy. Nature. 615(7950):158-167
2. Wang CJ, et al. (2022) Costimulation blockade in combination with IL-2 permits regulatory T cell sparing immunomodulation that inhibits autoimmunity. Nat Commun.13(1):6757.
3. van de Ven K, et al. (2022) A universal influenza mRNA vaccine candidate boosts T cell responses and reduces zoonotic influenza virus disease in ferrets. Sci Adv. 8(50):eadc9937.

Lympholyte®-Mammal

1. Ye D, et al. (2024) RAGE in circulating immune cells is fundamental for hippocampal inflammation and cognitive decline in a mouse model of latent chronic inflammation. Brain Behav lmmun. 116:329-348.
2. Gorman J, et al. (2024) Cleavage-intermediate Lassa virus trimer elicits neutralizing responses, identifies neutralizing nanobodies, and reveals an apex-situated site-of-vulnerability. Nat Commun. 15(1):285.
3. Rotolo A, et al. (2023) Unedited allogeneic iNKT cells show extended persistence in MHC-mismatched canine recipients. Cell Rep Med. 4(10):101241.

Lympholyte®-Rabblt

1. Lassauniere R, et al. (2023) Preclinical evaluation of a SARS-CoV-2 variant B.1.351-based candidate DNA vaccine. Vaccine. 41(43):6505-6513.
2. Takeuchi Y, et al. (2017) Ulcer healing effect of autologous mixed sheets consisting of fibroblasts and peripheral blood mononuclear cells in rabbit ischemic hind limb. Am J Transl Res. 9(5):2340-2351.

Lympholyte®-R

1. Walker VE, et al. (2020) Analysis of DNA Adducts and Mutagenic Potency and Specificity in Rats Exposed to Acrylonitrile. Chem Res Toxicol. 33(7):1609-1622.
2. Rabani R, et al. (2018) Mesenchymal stem cells enhance NOX2-dependent reactive oxygen species production and bacterial killing in macrophages during sepsis. Eur Respir J. 51(4):1702021.

Lympholyte®-H

1. Sardina F, et al. (2023) New cellular imaging-based method to distinguish the SPG4 subtype of hereditary spastic paraplegia. Eur J Neurol. 30(6):1734-1744.
2. Capitani N, et al. (2022) A CVID-associated variant in the ciliogenesis protein CCDC28B disrupts immune synapse assembly. Cell Death Differ. 29(1):65-81.
3. Evgin L, et al. (2022) Oncolytic virus-mediated expansion of dual-specific CAR T cells improves efficacy against solid tumors in mice. Sci Transl Med.14(640):eabn2231.
4. Liu YC, et al. (2022) Demethylation and Up-Regulation of an Oncogene after Hypomethylating Therapy. N Engl J Med. 386(21):1998-2010.
5. Ye C, et al. (2022) Single-cell and spatial transcriptomics reveal the fibrosis-related immune landscape of biliary atresia. Clin Transl Med.12(11):e1070.

Lympholyte®-1.1

1. Kim YK, et al. (2022) Zinc transporter 8 haploinsufficiency protects against beta cell dysfunction in type 1 diabetes by increasing mitochondrial respiration. Mal Metab. 66:101632.
2. Jamison BL, et al. (2022) Tolerogenic Delivery of a Hybrid Insulin Peptide Markedly Prolongs Islet Graft Survival in the NOD Mouse. Diabetes. 71(3):483-496.