インターフェロンタンパク質

製品使用文献(一部)

Human IFN-Alpha 2 Protein (品番：11100)

1. Lee, AM. et al., (2023), "Neutrophil-plasmacytoid dendritic cell interaction leads to production of type I IFN in response to Mycobacterium tuberculosis", Eur J Immunol., e2350666, PMID: 38161237, DOI: 10.1002/eji.202350666 (link)
2. Lai, JH. et al., (2023), "USP18 enhances dengue virus replication by regulating mitochindrial DNA release", Sci Rep. 13(1):20126, PMID: 37978268, DOI: 10.1038/s41598-023-47584-w (link)
3. Cacace, R. et al., (2023), "Mutated Toll-like receptor 9 increases Alzheimer's disease risk by compromising innate immunity protection", Mol. Psychiatry, PIMID: 37433968, DOI: 10.1038/s41380-023-02166-0 (link)
4. Laurent, P. et al., (2022), "Sensing of SARS-CoV-2 by pDCs and their subsequent production of IFN-I contribute to macrophage-induced cytokine storm during COVID-19", Sci Immunol., 7(75):eadd4906, PMID: 36083891, DOI: 10.1126/sciimmunol.add4906 (link)
5. Zhang, Q., et al.,(2022), "Autoantibodies against type I IFNs in patients with critical influenza pneumonia", J. Exp. Med. 219(11):e20220514, DOI: 10.1084/jem.20220514 (link)

Human IFN-Alpha 2b Protein (品番：11105)

1. Zhu,, G. et al., (2023),"Type I Interferonopathy due to a Homozygous Loss-of-Inhibitory Function Mutation in STAT2", J. Clin. Immunol., PMID: 36753016, DOI: 10.1007/s10875-023-01445-3 (link)
2. Quellec, J. et al., (2023), "Rift Valley fever virus modulates apoptosis and immune response during infection of human astrocytes", Emerg Microbes Infect., PMID: 37306630, DOI: 10.1080/22221751.2023.2207672 (link)
3. Barer, L. et al., (2023), "Lipocalin-2 regulates the expression of interferon-stimulated genes and the susceptibility of prostate cancer cells to oncolytic virus infection", Euro. J. Cell Biol., DOI: 10.1016/j. ejcb.2023.151328 (link)
4. Singh, M., et al., (2021), "A virus-derived microRNA targets immune response genes during SARS-CoV-2 infection", EMBO Reports, e54341, DOI:10.15252/embr.202154341 (link)
5. He, et al. (2019). A Human Papillomavirus-Independent Cervical Cancer Animal Model Reveals Unconventional Mechanisms of Cervical Carcinogenesis. Cell Reports. PMID: 30840887. (link)

Universal Type I IFN (Human IFN-Alpha Hybrid Protein) (品番：11200)

1. Reiter, S. et al., (2024), "Development of rhesus macaque astrocyte cell lines supporting infection with a panel of viruses", PLoS One, 19(5):e0303059, PMID: 38743751, DOI: 10.1371/journal.pone.0303059 (link)
2. Eisfeld, A.J. et al., (2024), "A compendium of multi-omics data illuminating host responses to lethal human virus infections", Sci Data., 11(1):328, PMID: 38565538, DOI: 10.1038/s41597-024-03124-3 (link)
3. Lei, X. et al., (2024), "CD4+T cells produce IFN-I to license cDC1s for induction of cytotoxic T-cell activity in human tumors", Cell Mol Immunol., PMID: 38383773, DOI: 10.1038/s41423-024-01133-1 (link)
4. Miyauchi, S. et al., (2023), "Reprogramming of tumor-associated macrophages via NEDD4-mediated CSF1R degradation by targeting USP8", Cell Rep., 42(12):113560, PMID: 38100351, DOI: 10.1016/j.celrep.2023.113560 (link)
5. Shu, J., et al., (2023), "Zika virus infection triggers caspase cleavage of STAT1", Microbiol Spectr., e0360923, PMID: 38018976, DOI: 10.1128/spectrum.03609-23 (link)

Human IFN-Beta Protein, mammalian expressed, carrier free (品番：11410)

1. Pelz, A. et al., (2023), "Broad-Spectrum Antiviral of Influenza A Defective Interfering Particles against Respiratory Syncytial, Yellow fever, and Zika Virus Replication In Vitro", Viruses, 15(9):1872, DOI: 10.3390/v15091872 (link)
2. Kurland, A.P. et al., (2023), "A Chemical Proteomics Approach to Discover Regulators of Innate Immune Signaling", Viruses, 15(5):1112, DOI: 10.3390/v15051112 (link)
3. Iyer, Shilpa, et al. (2017). Resistance to Type I Interferons is a Major Determinant of HIV-1 Transmission Fitness. PNAS, 10 pgs. PMID: 28069935. (link)
4. Bowen, James, et al. (2017). Zika Virus Antagonizes Type I Interferon Responses During Infection of Human Dendritic Cells. PLOS Pathogens, 30 pgs. PMID: 28152048. (link)

Human IFN-Beta Protein, mammalian expressed (品番：11415)

1. Eisfeld, A.J. et al., (2024), "A compendium of multi-omics data illuminating host responses to lethal human virus infections", Sci Data., 11(1):328, PMID: 38565538, DOI: 10.1038/s41597-024-03124-3 (link)
2. Lai, JH. et al., (2023), "USP18 enhances dengue virus replication by regulating mitochindrial DNA release", Sci Rep. 13(1):20126, PMID: 37978268, DOI: 10.1038/s41598-023-47584-w (link)
3. Sato, Y. et al., (2022), "Epstein-Barr virus tegument protein BGLF2 in exosomes released from virus-producing cells facilitates de novo infection", Cell Commun. Signal., 20(1):95, PMID: 35729616, DOI: 10.1186/s12964-022-00902-7 (link)
4. Timilsina, U. et al., (2022), "SARS-CoV-2 ORF7a potently inhibits the antiviral effect of the host factor SERINC5", Nat. Commun., 13(1):2935, PMID: 35618710, DOI: 10.1038/s41467-022-30690-9 (link)
5. Campbell, T. G. et al.,  (2022), "Respiratory viral infections in otherwise healthy humans with inherited IRF7 deficiency", JEM, 219(7):e20220202, PMID:35670811, DOI: 10.1084/jem.20220202 (link)

Mouse IFN-Alpha Protein (品番：12100)

1. Cai, Q. et al., (2024), "Interferon-stimulated gene PVRL4 broadly suppresses viral entry by inhibiting viral-cellular membrane fusion", Cell Biosci., 14(1):23, PMID: 38368366, DOI: 10.1186/s13578-024-01202-y (link)
2. Lai, JH. et al., (2023), "USP18 enhances dengue virus replication by regulating mitochindrial DNA release", Sci Rep. 13(1):20126, PMID: 37978268, DOI: 10.1038/s41598-023-47584-w (link)
3. Ugur, M. et al., (2023), "Lymph node medulla regulates the spatiotemporal unfolding of resident dendritic cell networks", Immunity, S1074-7613(23)00277-7, PMID: 37463581, DOI: 10.1016/j.immuni.2023.06.020 (link)
4. Zhang, T., et al., (2022), "Mesenchymal stromal cells equipped by IFNa empower T cells with potent anti-tumor immunity", Oncogene, PMID: 35145233, DOI: 10.1038/s41388-022-02201-4 (link)
5. Zhang et al., (2020), "Type I interferon signaling mediates Mycobacterium tuberculosis-induced macrophage death", JEM 218(2), PMID: 33125053 (link)

Mouse IFN-Beta Protein (品番：12400)

1. Choy, L. et al., (2024), "Inhibition of Aurora kinase induces endogenous retroelements to induce a type I/III interferon response via RIG-I:, Cancer Res Commun. PMID: 38358346, DOI: 10.1158/2767-9764.CRC-23-0432 (link)
2. Baran, M. et. al.,  (2023), "PYHIN protein IFI207 regulates cytokine transcription and IRF7 and contributes to the establishment of K. pneumoniae infection", Cell Rep.,  42(4):112341, PMID: 37018072, DOI: 10.1016/j.celrep.2023.112341 (link)
3. Zhu, J. et al., (2022), "LincRNA-EPS impairs host antiviral immunity by antagonizing viral RNA-PKR interaction", EMBO Reports, e53937, PMID: 35312340, DOI: 0.15252/embr.202153937 (link)
4. Panagioti, E., et al., (2021), Immunostimulatory bacterical antigen-armed oncolytic measles virotherapy significantly increases the potency of anti-PD1 checkpoint therapy, J.Clin. Invest., 131(10):e141614, DOI: 10.1172/JCI141614 (link)