記事ID ： 10671

HepG2 ヒト肝癌由来細胞株 & 専用培地

メーカー名：Cellular Engineering Technologies, Inc.

ヒト肝癌由来細胞株であるHepG2細胞は、長年にわたり肝臓の代替モデルとして、発癌研究、毒性評価、抗癌剤候補物のスクリーニング、シグナル伝達研究、分子生物学研究等の幅広い研究分野で使用されております。
Cellular Enginerring Technologies社のHepG2細胞は優れた増殖能を持っています。

HepG2 ヒト肝癌細胞

増殖特性	Adherent
ドナー	14 years old, Male, Caucasian
核型(Karyotype)	Modal number = 55 (range = 50 to 60); has a rearranged chromosome 1
腫瘍原性	No：immunosuppressed mice　Yes：in semisolid medium
発現遺伝子	alpha-fetoprotein (AFP, alpha-fetoprotein); albumin; alpha2 macroglobulin (alpha-2-macroglobulin); alpha1 antitrypsin (alpha-1-antitrypsin); transferrin; alpha1 antichymotrypsin (alpha-1-antichymotrypsin); haptoglobin; ceruloplasmin; plasminogen, complement (C4); C3 activator; fibrinogen; alpha1 acid glycoprotein (alpha-1 acid glycoprotein); alpha2 HS glycoprotein (alpha-2-HS-glycoprotein); beta lipoprotein (beta-lipoprotein); retinol binding protein (retinol-binding protein)
発現マーカー	Insulin: insulin-like growth factor II (IGF II)

参考文献

Kimura, T et al. Thrombospondin 2 is a Key Determinant of Fibrogenesis in Non-Alcoholic Fatty Liver Disease. Liver International 2024 FEB.
Ikeda, K et al. Comparison of Amine-Modified Polymeric Stationary Phases for Polar Metabolomic Analysis Based on Unified-Hydrophilic Interaction/Anion Exchange Liquid Chromatography/High-Resolution Mass Spectrometry (Unified-HILIC/AEX/HRMS). Mass Spectrometry 2024 JAN.
Tomioka, D et al. Hydroxyapatite Nanocoating on Calcium Peroxide Microparticles for Sustained Oxygen Release. Chemistry of Materials 2023, 35,5378－5391
Udagawa, D et al. Decellularized liver hydrogel enhances cell engraftment in orthotopic hepatocyte transplantation by promoting cell-cell interaction and angiogenesis. Research Square 2023 MAY.
Tani, N et al. Relationship between clock gene expression and CYP2C19 and CYP3A4 with benzodiazepines. Human & Experimental Toxicology 2023 APR.
Tani, N et al. Effect of methamphetamine on clock genes and drug-metabolizing enzyme expression. Human & Experimental Toxicology 2022 AUG

HepG2 ヒト肝癌由来細胞株

品名	メーカー	品番	包装	希望販売価格
HepG2 Hepatocellular Carcinoma Cells, Human	CET	CR1015-500	1 VIAL [>500,000 cells]	￥126,000

専用培地

HepG2細胞の培養用に最適にデザインされた培地です。細胞とのセット品 (品番：BR1003) もございます。

品名	メーカー	品番	包装	希望販売価格
HepG2 Hepatocellular Carcinoma Expansion Media, Human	CET	MR1010	1 BOTTLE [450 mL]	￥95,000
HepG2 Research Bundle, Human	CET	BR1003	1 SET [>500,000 cells, 450mL]	￥198,000