記事ID ： 44053

卵巣がんマーカー抗体

メーカー名：Atlas Antibodies AB

　婦人科系のがんは、女性の生殖器官に発生するがんです。婦人科系のがんは、子宮頸がん、卵巣がん、子宮体がん、腟がん、外陰がんの5種類に大別されます。このうち卵巣がんは、女性の生殖器系のがんの中で最も死亡率の高いがんであり、患者の約3分の2が進行した状態で発見されるため、晩発性がんとして知られています。さらに、約90％の患者が再発を繰り返し、最終的には化学療法抵抗性となります。そのため、早期発見のためのスクリーニングや新たな治療標的として、本疾患に特異的なバイオマーカーを同定することが強く望まれています。これらのバイオマーカーが卵巣がんの存在、病期、治療効果を予測することができれば、卵巣がん患者の早期診断と生存率の向上が期待されます。Atlas Antibodies（ATL）社は、より優れた早期発見マーカーと新たな治療標的の探索を続けています。

図 1. 女性の生殖管と卵巣がんの種類の模式図
卵巣がんは、由来する細胞の種類、つまり卵巣を構成する 3 つの主な細胞の種類 (生殖細胞、間質、上皮) にちなんで名付けられています。上皮癌には、小細胞がん、生殖細胞がん、性索間質がん、および漿液性がん（高悪性度および低悪性度）が含まれます。

卵巣がんマーカーカタログ

商品名	タンパク質名	品番	アイソタイプ	適用
Anti-BIRC5	Baculoviral IAP repeat-containing protein 5	AMAb91761	IgG1	WB
Anti-CALB2	Calbindin 2	AMAb91812	IgG1	IHC, WB
Anti-CALB2	Calbindin 2	AMAb91813	IgG2a	IHC*
Anti-CALB2	Calbindin 2	AMAb91814	IgG1	IHC, WB
Anti-CD44	CD44 antigen	AMAb91845	IgG3	IHC, WB
Anti-CD44	CD44 antigen	AMAb91846	IgG2a	IHC, WB
Anti-CD44	CD44 antigen	AMAb91847	IgG2b	IHC, WB
Anti-CD44	CD44 antigen	AMAb91848	IgG1	IHC, WB
Anti-CD99 (MIC2)	Cd99 molecule (xg blood group)	AMAb91823	IgG2a	IHC
Anti-CDKN1A (p21)	Cyclin-dependent kinase inhibitor 1	AMAb91832	IgG1	WB, ICC-IF
Anti-CDX2	Caudal type homeobox 2	AMAb91827	IgG1	IHC, WB, ICC-IF
Anti-CLDN3	Claudin-3	AMAb91834	IgG1	IHC, WB, ICC-IF
Anti-CLDN3	Claudin-3	AMAb91835	IgG2a	IHC, WB, ICC-IF
Anti-CLDN3	Claudin-3	AMAb91836	IgG2b	IHC, WB, ICC-IF
Anti-FOXL2	Forkhead box protein L2	AMAb91808	IgG3	IHC*, WB
Anti-FOXL2	Forkhead box protein L2	AMAb91809	IgG1	IHC*
Anti-FOXO1	Forkhead box protein O1	AMAb91844	IgG1	WB*
Anti-GPC3	Glypican 3	AMAb91803	IgG2b	IHC*
Anti-GSPT1	G1 to s phase transition 1	AMAb91849	IgG2a	IHC, WB
Anti-GSPT1	G1 to s phase transition 1	AMAb91851	IgG2a	IHC, WB, ICC-IF
Anti-L1CAM (CD171)	Neural cell adhesion molecule L1	AMAb91829	IgG2a	IHC*
Anti-L1CAM (CD171)	Neural cell adhesion molecule L1	AMAb91830	IgG1	IHC*
Anti-MCAM (CD146)	Cell surface glycoprotein MUC18	AMAb91815	IgG1	IHC*
Anti-MLANA	Melanoma antigen	AMAb91816	IgG1	IHC, WB, ICC-IF
Anti-MLANA	Melanoma antigen	AMAb91817	IgG1	IHC, WB, ICC-IF
Anti-MLANA	Melanoma antigen	AMAb91818	IgG1	IHC, WB, ICC-IF
Anti-NAPSA	Napsin-A aspartic peptidase	AMAb91825	IgG1	IHC*
Anti-NCAM1 (CD56)	Neural cell adhesion molecule 1	AMAb91807	IgG2b	IHC*
Anti-SLC18A2 (VMAT2)	Solute carrier family 18 member a2	AMAb91837	IgG2b	IHC
Anti-SLC18A2 (VMAT2)	Solute carrier family 18 member a2	AMAb91838	IgG1	IHC, WB
Anti-TFE3	Transcription factor E3	AMAb91798	IgG2b	IHC, WB
Anti-TFE3	Transcription factor E3	AMAb91799	IgG1	IHC, WB, ICC-IF
Anti-TMPRSS2	Transmembrane protease serine 2	AMAb91792	IgG1	IHC*
Anti-TMPRSS2	Transmembrane protease serine 2	AMAb91793	IgG1	IHC*
Anti-TMPRSS2	Transmembrane protease serine 2	AMAb91795	IgG2a	IHC*
Anti-TNFRSF8	Tnf receptor superfamily member 8	AMAb91800	IgG2a	IHC
Anti-TSPO	Translocator protein	AMAb91853	IgG2b	IHC, WB, ICC-IF
Anti-TSPO	Translocator protein	AMAb91854	IgG2a	IHC, WB, ICC-IF
Anti-WFDC2	Wap four-disulfide core domain 2	AMAb91819	IgG1	IHC*
Anti-WFDC2	Wap four-disulfide core domain 2	AMAb91821	IgG1	IHC*
Anti-WT1	Wilms tumor protein	AMAb91839	IgG2b	IHC, WB, ICC-IF
Anti-WT1	Wilms tumor protein	AMAb91840	IgG2a	IHC, WB, ICC-IF
Anti-WT1	Wilms tumor protein	AMAb91842	IgG1	IHC, WB, ICC-IF

※「Enhanced バリデーション」が実施された適用です。「Enhanced バリデーション」では、Nature Methods 誌に掲載された the International Working Group for Antibody Validation (IWGAV) のガイドラインに従って実施されています。
詳細はこちらからご覧いただけます。

卵巣がんマーカー抗体

品名	メーカー	品番	包装	希望販売価格
Anti BIRC5, (Mouse) , CL12064	ATL	AMAB91761	100 UL [1.0 mg/ml]	￥95,000
Anti CALB2, (Mouse) , CL12836	ATL	AMAB91812	100 UL [1.0 mg/ml]	￥112,000
Anti CALB2, (Mouse) , CL12838	ATL	AMAB91813	100 UL [1.0 mg/ml]	￥112,000
Anti CALB2, (Mouse) , CL12842	ATL	AMAB91814	100 UL [1.0 mg/ml]	￥112,000
Anti CD44, (Mouse) , CL13318	ATL	AMAB91845	100 UL [1.0 mg/ml]	￥95,000
Anti CD44, (Mouse) , CL13319	ATL	AMAB91846	100 UL [1.0 mg/ml]	￥95,000
Anti CD44, (Mouse) , CL13324	ATL	AMAB91847	100 UL [1.0 mg/ml]	￥95,000
Anti CD44, (Mouse) , CL13328	ATL	AMAB91848	100 UL [1.0 mg/ml]	￥95,000
Anti CD99, (Mouse) , CL12929	ATL	AMAB91823	100 UL [1.0 mg/ml]	￥112,000
Anti CDKN1A, (Mouse) , CL13081	ATL	AMAB91832	100 UL [1.0 mg/ml]	￥95,000
Anti CDX2, (Mouse) , CL12967	ATL	AMAB91827	100 UL [0.5 mg/ml]	￥95,000
Anti CLDN3, (Mouse) , CL13128	ATL	AMAB91834	100 UL [1.0 mg/ml]	￥112,000
Anti CLDN3, (Mouse) , CL13129	ATL	AMAB91835	100 UL [1.0 mg/ml]	￥112,000
Anti CLDN3, (Mouse) , CL13130	ATL	AMAB91836	100 UL [1.0 mg/ml]	￥112,000
Anti FOXL2, (Mouse) , CL12753	ATL	AMAB91808	100 UL [1.0 mg/ml]	￥112,000
Anti FOXL2, (Mouse) , CL12762	ATL	AMAB91809	100 UL [1.0 mg/ml]	￥112,000
Anti FOXO1, (Mouse) , CL13278	ATL	AMAB91844	100 UL [1.0 mg/ml]	￥95,000
Anti GPC3, (Mouse) , CL12711	ATL	AMAB91803	100 UL [1.0 mg/ml]	￥112,000
Anti GSPT1, (Mouse) , CL13332	ATL	AMAB91849	100 UL [1.0 mg/ml]	￥119,000
Anti GSPT1, (Mouse) , CL13336	ATL	AMAB91851	100 UL [1.0 mg/ml]	￥119,000
Anti L1CAM, (Mouse) , CL12984	ATL	AMAB91829	100 UL [1.0 mg/ml]	￥112,000
Anti L1CAM, (Mouse) , CL12988	ATL	AMAB91830	100 UL [1.0 mg/ml]	￥112,000
Anti MCAM, (Mouse) , CL12855	ATL	AMAB91815	100 UL [1.0 mg/ml]	￥95,000
Anti MLANA, (Mouse) , CL12863	ATL	AMAB91816	100 UL [1.0 mg/ml]	￥112,000
Anti MLANA, (Mouse) , CL12864	ATL	AMAB91817	100 UL [1.0 mg/ml]	￥112,000
Anti MLANA, (Mouse) , CL12874	ATL	AMAB91818	100 UL [1.0 mg/ml]	￥112,000
Anti NAPSA, (Mouse) , CL12954	ATL	AMAB91825	100 UL [1.0 mg/ml]	￥112,000
Anti NCAM1, (Mouse) , CL12732	ATL	AMAB91807	100 UL [1.0 mg/ml]	￥95,000
Anti SLC18A2, (Mouse) , CL12531	ATL	AMAB91837	100 UL [0.7 mg/ml]	￥112,000
Anti SLC18A2, (Mouse) , CL13157	ATL	AMAB91838	100 UL [1.0 mg/ml]	￥112,000
Anti TFE3, (Mouse) , CL12810	ATL	AMAB91798	100 UL [0.9 mg/ml]	￥112,000
Anti TFE3, (Mouse) , CL12822	ATL	AMAB91799	100 UL [1.0 mg/ml]	￥112,000
Anti TMPRSS2, (Mouse) , CL12511	ATL	AMAB91792	100 UL [0.7 mg/ml]	￥112,000
Anti TMPRSS2, (Mouse) , CL12512	ATL	AMAB91793	100 UL [1.0 mg/ml]	￥112,000
Anti TMPRSS2, (Mouse) , CL12514	ATL	AMAB91795	100 UL [0.5 mg/ml]	￥112,000
Anti TNFRSF8, (Mouse) , CL12632	ATL	AMAB91800	100 UL [1.0 mg/ml]	￥95,000
Anti TSPO, (Mouse) , CL13358	ATL	AMAB91853	100 UL [1.0 mg/ml]	￥112,000
Anti TSPO, (Mouse) , CL13359	ATL	AMAB91854	100 UL [1.0 mg/ml]	￥112,000
Anti WFDC2, (Mouse) , CL12886	ATL	AMAB91819	100 UL [1.0 mg/ml]	￥112,000
Anti WFDC2, (Mouse) , CL12917	ATL	AMAB91821	100 UL [0.8 mg/ml]	￥112,000
Anti WT1, (Mouse) , CL13165	ATL	AMAB91839	100 UL [1.0 mg/ml]	￥95,000
Anti WT1, (Mouse) , CL13170	ATL	AMAB91840	100 UL [1.0 mg/ml]	￥95,000
Anti WT1, (Mouse) , CL13176	ATL	AMAB91842	100 UL [0.8 mg/ml]	￥95,000