101 Bio社では、様々なサンプルから高純度なエクソソームを単離・回収するための一連のキットを販売しております。
エクソソーム研究製品一覧
品番 | 品名 | アプリケーション | ||||
---|---|---|---|---|---|---|
P100 | エクソソーム単離 - 細胞 | 細胞培養上清 | ![]() |
エクソソーム | ||
P101 | エクソソーム単離 - 血清 | 血清/血漿 | ![]() |
エクソソーム | ||
P107 | エクソソーム単離 - 幹細胞 | 幹細胞培養上清 | ![]() |
エクソソーム | ||
P120 | エクソソーム単離 - 尿 | 尿 | ![]() |
エクソソーム | ||
P121 | エクソソーム単離 - 体液 | 生体液試料 | ![]() |
エクソソーム | ||
P130 | Exosome-TEM-easy Kit | 透過型電子顕微鏡(TEM)用エクソソームサンプル調製キット | ||||
P140 | ヒト由来エクソソーム - 正常 |
|||||
P141 | ヒト由来エクソソーム - 乳癌患者 |
|||||
P200 | エクソソームRNA/タンパク質抽出 | エクソソーム | ![]() |
RNA/タンパク質 | ||
P201 | 界面活性剤フリー エクソソームタンパク質抽出 |
エクソソーム | ![]() |
界面活性剤フリー タンパク質 |
||
P230 | エクソソームDNA抽出 | エクソソーム | ![]() |
DNA | ||
P300 | エクソソームタンパク質抽出 - 血清/血漿 |
血清/血漿 | ![]() |
エクソソーム 由来タンパク質 |
||
P400 | エクソソームにRNA導入 - エレクトロポレーション |
small RNA | into![]() |
エクソソーム | ||
P401 | エクソソームにRNA導入 - トランスフェクション |
small RNA | into![]() |
エクソソーム |
■ 幅広い製品ラインアップ

■ 優れた性能
101Bio社 | 他社1 | 他社2 | |
---|---|---|---|
単離エクソソームの純度 | 高 (>95%) |
低 | 低 |
エクソソームの収量 | 10 x | 1 x | 1 x |
Small RNA のトランスフェクション可否 | 可 | 不可 | 不可 |
■ 良好な粒径分布
製品使用文献
【PureExo® エクソソーム単離キット(細胞培養上清用#P100)】
- Osteikoetxea X, Németh A, Sódar BW, Vukman KV, Buzás EI. Extracellular vesicles in cardiovascular diseases, are they Jedi or Sith? J Physiol. 2016 Feb 13. doi: 10.1113/JP271336
- Korbelik M, Banáth J, Zhang W, Wong F, Bielawski J, Separovic D. Ceramide and Sphingosine-1-Phosphate/Sphingosine act as Photodynamic Therapy-Elicited Damage-Associated Molecular Patterns: Release from Cells and Impact on Tumor-Associated Macrophages. J Anal Bioanal Tech. S1:009. doi: 10.4172/2155-9872.S1-009 (2014)
- Salama A, Fichou N, Allard M, Dubreil L, De Beaurepaire L, Viel A, Jégou D, Bösch S, Bach JM. MicroRNA-29b modulates innate and antigen-specific immune responses in mouse models of autoimmunity. PLoS One. 2014 Sep 9;9(9):e106153. doi: 10.1371/journal.pone.0106153.
- Mar?dziak M, Marycz K, Lewandowski D, Siudzi?ska A, ?mieszek A. Static magnetic field enhances synthesis and secretion of membrane-derived microvesicles (MVs) rich in VEGF and BMP-2 in equine adipose-derived stromal cells (EqASCs)-a new approach in veterinary regenerative medicine. In Vitro Cell Dev Biol Anim. 2015 Mar;51(3):230-40. doi: 10.1007/s11626-014-9828-0.
- Tomoyo Kawakubo-Yasukochi, Masahiko Morioka, Yoshikazu Hayashi, Takuya Nishinakagawa, Mai Hazekawa, Shintaro Kawano, Seiji Nakamura, Manabu Nakashima The SQUU-B cell line spreads its metastatic properties to nonmetastatic clone SQUU-A from the same patient through exosomes. J of Oral Biosciences 2015/09
PureExo® citation from Japan distributor Cosmo indicates interesting exosome function: "exosome derived from highly metastatic SQUU-B cells conferred metastatic ability to nonmetastatic SQUU-A cells." - William G. Whitford Exosomes: A Major Phenomenon Flying Under the Radar cellculturedish.com 2015/09
- Bonafede R, Scambi I, Peroni D, Potrich V, Boschi F, Benati D, Bonetti B, Mariotti R. Exosome derived from murine adipose-derived stromal cells: Neuroprotective effect on in vitro model of amyotrophic lateral sclerosis. Exp Cell Res. 2016 Jan 1;340(1):150-8. doi: 10.1016/j.yexcr.2015.12.009. Epub 2015 Dec 18.
- Zhou Y, Fang L, Yu Y, Niu J, Jiang L, Cao H, Sun Q, Zen K, Dai C, Yang J. Erythropoietin protects the tubular basement membrane by promoting the bone marrow to release extracellular vesicles containing tPA-targeting miR-144. Am J Physiol Renal Physiol. 2016 Jan 1;310(1):F27-40. doi: 10.1152/ajprenal.00303.2015. Epub 2015 Oct 14.
- Campbell CR, Berman AE, Weintraub NL, Tang YL. Electrical stimulation to optimize cardioprotective exosomes from cardiac stem cells. Med Hypotheses. 2016 Mar;88:6-9. doi: 10.1016/j.mehy.2015.12.022. Epub 2016 Jan 11.
- Zhu D, Liu Z, Wang F. Effect of exosome extracted from 3T3 on proliferation of mouse colorectal cancer cells CT26. Chin J of Exp Surg. 2015 July;32(7):1634-36
- Rager T, Olson J, Zhou Y, Wang Y, Besner G. Exosomes Secreted from Bone Marrow-Derived Mesenchymal Stem Cells Protect the Intestines from Experimental Necrotizing Enterocolitis. J Pediatr Surg. 2016 March;S0022-3468(16)00149-4
- Li X, Liu L, Yang J, Yu Y, Chai J, Wang L, Ma L, Yin H. Exosome Derived From Human Umbilical Cord Mesenchymal Stem Cell Mediates MiR-181c Attenuating Burn-induced Excessive Inflammation. EBioMedicine. 2016, http://dx.doi.org/10.1016/j.ebiom.2016.04.030
- Masahiko Morioka, Tomoyo Kawakubo-Yasukochi, Yoshikazu Hayashi, Mai Hazekawa, Takuya Nishinakagawa, Kazuhiko Ono, Shintaro Kawano, Seiji Nakamura, Manabu Nakashima. Exosomes from oral squamous carcinoma cell lines, SQUU-A and SQUU-B, define the tropism of lymphatic dissemination. J of Oral Biosciences. 2016, http://dx.doi.org/10.1016/j.job.2016.05.001i
【PureExo® エクソソーム単離キット(血清/血漿用#P101)】
- Chen L, Chen R, Kemper S, Charrier A, Brigstock DR. Suppression of fibrogenic signaling in hepatic stellate cells by Twist1-dependent microRNA-214 expression: Role of exosomes in horizontal transfer of Twist1. Am J Physiol Gastrointest Liver Physiol. 2015 Sep 15;309(6):G491-9. doi: 10.1152/ajpgi.00140.2015. Epub 2015 Jul 30.
This paper is awarded TOP 10 best original research papers published by the American Physiological Society (APS Select).
(APSselect is a collection of the very best original research papers published by the American Physiological Society. Each month, the most outstanding recently published papers from our ten research journals are selected and made available through this multi-journal website.) - Osteikoetxea X, Németh A, Sódar BW, Vukman KV, Buzás EI. Extracellular vesicles in cardiovascular diseases, are they Jedi or Sith? J Physiol. 2016 Feb 13. doi: 10.1113/JP271336
- William G. Whitford Exosomes: A Major Phenomenon Flying Under the Radar cellculturedish.com 2015/09
- Chen L., Chen R., Brigstock D. MicroRNA profiling of circulating exosomes during experimental liver fibrosis. Hepatology. AASLD abstract, 2014 Oct. (Presidential Honored Distinct Abstract).
【sRNA-into-Exosome Kit(Chemical)(#P401)】
- Salama A, Fichou N, Allard M, Dubreil L, De Beaurepaire L, Viel A, Jégou D, Bösch S, Bach JM. MicroRNA-29b modulates innate and antigen-specific immune responses in mouse models of autoimmunity. PLoS One. 2014 Sep 9;9(9):e106153. doi: 10.1371/journal.pone.0106153.
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